新アルゴリズムでCovid-19の波のパラメータを設定(New algorithm sets parameters for waves of Covid-19)

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2023-06-05 カーディフ大学

◆カーディフ大学とオックスフォード大学の研究者は、新型コロナウイルスの感染と死亡のデータを分析するアルゴリズムを開発しました。これにより、病気の波を特定し理解することができます。アルゴリズムは、長期間で深刻な感染がある場合を意味のある波とし、一時的な変動は無視します。
◆この研究は政策立案者や公衆衛生専門家に将来の流行やパンデミックへの対策を支援します。また、地理的な変動や政府の介入の影響も明らかになりました。

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疫学の波 – COVID-19パンデミックにおけるタイプ、ドライバー、モジュレーター。 Epidemiological waves – Types, drivers and modulators in the COVID-19 pandemic

John Harvey,Bryan Chan,Tarun Srivastava,Alexander E. Zarebski,Paweł Dłotko,Piotr Błaszczyk,Rachel H. Parkinson,Lisa J. White,Ricardo Aguas,Adam Mahdi
Heliyon  Published:May 02, 2023
DOI:https://doi.org/10.1016/j.heliyon.2023.e16015

Fig. 1

Abstract

Introduction
A discussion of ‘waves’ of the COVID-19 epidemic in different countries is a part of the national conversation for many, but there is no hard and fast means of delineating these waves in the available data and their connection to waves in the sense of mathematical epidemiology is only tenuous.

Methods
We present an algorithm which processes a general time series to identify substantial, significant and sustained periods of increase in the value of the time series, which could reasonably be described as ‘observed waves’. This provides an objective means of describing observed waves in time series. We use this method to synthesize evidence across different countries to study types, drivers and modulators of waves.

Results
The output of the algorithm as applied to epidemiological time series related to COVID-19 corresponds to visual intuition and expert opinion. Inspecting the results of individual countries shows how consecutive observed waves can differ greatly with respect to the case fatality ratio. Furthermore, in large countries, a more detailed analysis shows that consecutive observed waves have different geographical ranges. We also show how waves can be modulated by government interventions and find that early implementation of NPIs correlates with a reduced number of observed waves and reduced mortality burden in those waves.

Conclusion
It is possible to identify observed waves of disease by algorithmic methods and the results can be fruitfully used to analyse the progression of the epidemic.

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