ロボティクスと脊髄刺激による麻痺患者の運動回復(Robotics and spinal stimulation restore movement in paralysis)

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20025-03-13 スイス連邦工科大学ローザンヌ校(EPFL)

ロボティクスと脊髄刺激による麻痺患者の運動回復(Robotics and spinal stimulation restore movement in paralysis)
Common robotic devices to safely automate and augment gait rehabilitation. © .NeuroRestore/EPFL/CHUV 2025

スイス連邦工科大学ローザンヌ校(EPFL)の.NeuroRestore研究所は、脊髄神経刺激とリハビリロボットを組み合わせ、脊髄損傷患者の運動機能を回復させる新技術を開発しました。従来のロボット療法では神経系の再訓練に限界がありましたが、この技術は埋め込み型刺激装置がリアルタイムで調整され、自然な筋肉活動を促進します。5人の患者を対象とした試験で即時的かつ持続的な効果が確認され、屋外での運動も可能となりました。この技術は、リハビリ環境の変革につながる可能性があります。

<関連情報>

脊髄神経調節によるリハビリテーションロボット工学の増強: 概念実証 Augmenting rehabilitation robotics with spinal cord neuromodulation: A proof of concept

Nicolas Hankov, Miroslav Caban, Robin Demesmaeker, Margaux Roulet, […], and Grégoire Courtine
Science Robotics  Published:12 Mar 2025

Abstract

Rehabilitation robotics aims to promote activity-dependent reorganization of the nervous system. However, people with paralysis cannot generate sufficient activity during robot-assisted rehabilitation and, consequently, do not benefit from these therapies. Here, we developed an implantable spinal cord neuroprosthesis operating in a closed loop to promote robust activity during walking and cycling assisted by robotic devices. This neuroprosthesis is device agnostic and designed for seamless implementation by nonexpert users. Preliminary evaluations in participants with paralysis showed that the neuroprosthesis enabled well-organized patterns of muscle activity during robot-assisted walking and cycling. A proof-of-concept study suggested that robot-assisted rehabilitation augmented by the neuroprosthesis promoted sustained neurological improvements. Moreover, the neuroprosthesis augmented recreational walking and cycling activities outdoors. Future clinical trials will have to confirm these findings in a broader population.

医療・健康
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