2025-09-19 中国科学院(CAS)
<関連情報>
- https://english.cas.cn/newsroom/research_news/chem/202509/t20250916_1054897.shtml
- https://www.science.org/doi/10.1126/science.adw6854
生体電子インターフェースのコンフォーマルラップのための動的応力解放を伴うドロップ印刷 Drop-printing with dynamic stress release for conformal wrap of bioelectronic interfaces
An Li, Wenjianlong Zhou, Huizeng Li, Wei Fang, […] , and Yanlin Song
Science Published:11 Sep 2025
DOI:https://doi.org/10.1126/science.adw6854
Editor’s summary
Wrapping of thin-film bioelectronic devices onto three-dimensional surfaces can lead to residual stress and device failure. Li et al. overcame this challenge by using droplets of water, water-gelatin mixtures, or buffer solutions as a dynamic lubricating layer to enable conformal wrapping of fragile, nonstretchable films onto intricate substrates such as skin, polymers, cells, and nerves. The droplet lets the device slide across the target substrate, allowing it to conform to the underlying shape. The authors demonstrated drop printing onto nerves and brain tissue, enabling light-controlled neuromodulation. —Marc S. Lavine
Abstract
Bioelectronic interfaces demonstrate promising applications in health monitoring, medical treatment, and augmented reality. However, conformally wrapping these film devices onto three-dimensional surfaces often leads to stress-induced damage. We propose a “drop-printing” strategy that enables damage-free film transfer using a droplet. The droplet acts as a lubricating layer between the film and the target surface, facilitating local sliding during shape-adaptive deformation. This mechanism prevents in-plane film stretching and reduces stress concentration. Even nonstretchable and fragile films can be intactly and accurately wrapped onto delicate surfaces, such as microscale microorganisms and optical fibers. Two-micrometer-thick silicon films, without any stretchable engineering, can form conformal neural-electronic interfaces by being drop-printed on nerves and brain tissue. The interfaces achieve light-controlled in vivo neuromodulation with high spatiotemporal resolution.
