2024-02-02 ワシントン大学セントルイス校
◆Singamaneniは機械工学および材料科学学科のLilyan&E. Lisle Hughes教授であり、Ramanはバイオメディカルエンジニアリング学科の教授です。この研究では、ナノ構造は光を吸収し、熱を生成する(光熱効果と呼ばれる)だけでなく、化学物質を需要に応じて貯蔵および放出するコンテナとして機能します。
<関連情報>
- https://source.wustl.edu/2024/02/locusts-sense-of-smell-boosted-with-custom-made-nanoparticles/
- https://www.nature.com/articles/s41565-023-01592-z
ナノニューロモジュレーションで昆虫の嗅覚能力を増強する Augmenting insect olfaction performance through nano-neuromodulation
Prashant Gupta,Rishabh Chandak,Avishek Debnath,Michael Traner,Brendan M. Watson,Hengbo Huang,Hamed Gholami Derami,Harsh Baldi,Shantanu Chakrabartty,Baranidharan Raman & Srikanth Singamaneni
Nature Nanotechnology Published:25 January 2024
DOI:https://doi.org/10.1038/s41565-023-01592-z
Abstract
Biological olfactory systems are highly sensitive and selective, often outperforming engineered chemical sensors in highly complex and dynamic environments. As a result, there is much interest in using biological systems to build sensors. However, approaches to read-out information from biological systems, especially neural signals, tend to be suboptimal due to the number of electrodes that can be used and where these can be placed. Here we aim to overcome this suboptimality in neural information read-out by using a nano-enabled neuromodulation strategy to augment insect olfaction-based chemical sensors. By harnessing the photothermal properties of nanostructures and releasing a select neuromodulator on demand, we show that the odour-evoked response from the interrogated regions of the insect olfactory system can not only be enhanced but can also improve odour identification.
