妊娠後期の大気汚染曝露がNICU入院リスクを増加 (Study: Air pollution exposure late in pregnancy increases NICU admission risk)

2025-02-13 バッファロー大学 (UB)

<関連情報>

• https://www.buffalo.edu/news/releases/2025/02/phiri-air-pollution-last-month-pregnancy.html
• https://www.nature.com/articles/s41598-024-84755-9

米国における新生児集中治療入院と衛星由来の大気汚染物質への曝露(2018年) Neonatal intensive care admissions and exposure to satellite-derived air pollutants in the United States, 2018

Yohane Vincent Abero Phiri,Timothy Canty,Carrie Nobles,Allison M. Ring,Jing Nie & Pauline Mendola
Scientific Reports  Published:02 January 2025
DOI:https://doi.org/10.1038/s41598-024-84755-9

Abstract

In the United States (US), neonatal intensive care units (NICUs) monitor and treat newborns for a variety of adverse health concerns including preterm status, respiratory distress and restricted growth. As such, NICU admission is an integrated measure of neonatal risk. We linked 2018 US national birth registry NICU admission data among singleton births with satellite and modelled air pollution levels for the month prior to birth to examine whether late-pregnancy exposure to ambient air pollutants is associated with adverse neonatal health outcomes. Regardless of season, higher ambient levels of nitrogen dioxide (NO₂) and fine particulate matter < 2.5 microns (PM_2.5) increased the likelihood of NICU admission 30–35% for NO₂ and 11–22% for PM_2.5 even after adjustment for parental characteristics. Results for ozone exposure were inconsistent with largely null or reduced risk except for summer months. Despite the relatively low-moderate US exposure levels, traffic-related pollutants near the end of pregnancy appear to increase overall adverse health risks for newborns, underscoring the need to reduce prenatal exposure to ambient pollutants.