2025-08-13 国立精神・神経医療研究センター
【研究概要図(イメージ)】

<関連情報>
- https://www.ncnp.go.jp/topics/detail.php?@uid=NMsd3uJSr2gfkXbs
- https://www.ncnp.go.jp/press_search/images/files/NCNP_PR_250813.pdf
- https://www.nature.com/articles/s41598-025-11190-9
聞こえない高周波成分を含む音を用いて自律神経系の調節機能を高める Enhancing the regulatory function of the autonomic nervous system using sounds with inaudible high-frequency components
Koto Jogasaki,Norie Kawai,Emi Nishina & Manabu Honda
Scientific Reports Published:23 July 2025
DOI:https://doi.org/10.1038/s41598-025-11190-9
Abstract
The dysregulation of the autonomic nervous system (ANS) activity notably contributes to the onset and progression of numerous diseases, including lifestyle-related and psychiatric disorders. This necessitates the development of effective nonpharmacological methods for regulating ANS function for therapeutic purposes and disease prevention. This study examined how the presence or absence of the inaudible high-frequency component (HFC) of sounds—which activates deep-brain structures—affects the ANS regulatory function. Under the N-back task condition, which requires concentration, exposure to sounds with HFC resulted in significantly higher sympathetic and parasympathetic nervous activities compared to sounds without HFC. Conversely, under the relaxation condition, the sounds with HFC significantly suppressed sympathetic nervous activity relative to sounds without HFC. Therefore, sounds with HFC may flexibly adjust the sympathetic and parasympathetic nervous activities based on situational demands.

