2025-12-18 ペンシルベニア州立大学(Penn State)
<関連情報>
- https://www.psu.edu/news/health-and-human-development/story/night-waking-impacts-cognitive-performance-regardless-sleep
- https://www.sleephealthjournal.org/article/S2352-7218(25)00265-7/fulltext
高齢者の地域ベースのサンプルにおける睡眠特性と日常の認知能力との個人内および個人間の関連性 Within- and between-person associations of sleep characteristics with daily cognitive performance in a community-based sample of older adults
Orfeu M. Buxton, PhD ∙ Qi Gao, PhD ∙ Jonathan G. Hakun, PhD ∙ … ∙ Martin J. Sliwinski, PhD ∙ Cuiling Wang, PhD ∙ Carol A. Derby, PhD …
Sleep Health Published:December 17, 2025
DOI:https://doi.org/10.1016/j.sleh.2025.11.010
Abstract
Objectives
Few studies have examined daily effects of sleep on cognition. This analysis examined both between-person and within-person associations of actigraphic sleep with daily cognitive performance ascertained via ecological momentary assessments.
Methods
Data are from community-residing, dementia-free older adults in the Einstein Aging Study (mean age 77.2 ± 4.7, 67.3% female, 47% non-Hispanic White, and 40% non-Hispanic Black) who were free of dementia. Over 16 days, participants wore wrist actigraphs and completed cognitive assessments six times daily using study-provided smartphones and completed overnight pulse oximetry. Brief cognitive tasks assessed four domains of cognitive function. Multilevel linear mixed-effect models assessed associations of sleep characteristics with cognitive performance. Data were aligned such that models addressed the relationship between a day’s sleep parameters and the next day’s cognitive performance, adjusted for demographics, depression, cardiovascular comorbidity, and sleep-disordered breathing.
Results
In adjusted models, between-person associations showed that higher average wake after sleep onset (WASO) was associated with slower average processing speed, worse working memory, and worse visual memory binding. Within-person effects showed that an individual’s processing speed was slower than usual on days following a night with greater-than-usual WASO. Sleep duration, timing, or naps were not associated with any of the cognitive tests.
Conclusions
Using ambulatory assessments in real-world environments, the results demonstrate short-term effects of sleep fragmentation (WASO) on processing speed the next day in dementia-free older adults. Better understanding short-term effects might identify individuals who may benefit from early interventions to prevent long-term cognitive decline.
