2024-08-07 カリフォルニア工科大学(Caltech)
<関連情報>
- https://www.caltech.edu/about/news/caltech-team-develops-first-noninvasive-method-to-continually-measure-true-blood-pressure
- https://academic.oup.com/pnasnexus/article/3/7/pgae252/7717708?login=false
非侵襲的連続血圧モニタリングのための共鳴ソノマトメトリー Resonance sonomanometry for noninvasive, continuous monitoring of blood pressure
Raymond Jimenez, Dominic Yurk, Steven Dell, Austin C Rutledge, Matt K Fu, William P Dempsey, Yaser Abu-Mostafa, Aditya Rajagopal, Alaina Brinley Rajagopal
PNAS Nexus Published:30 July 2024
DOI:https://doi.org/10.1093/pnasnexus/pgae252
Abstract
Cardiovascular disease is the leading cause of death worldwide. Existing methods for continuous, noninvasive blood pressure (BP) monitoring suffer from poor accuracy, uncomfortable form factors, or a need for frequent calibration, limiting their adoption. We introduce a new framework for continuous BP measurement that is noninvasive and calibration-free called resonance sonomanometry. The method uses ultrasound imaging to measure both the arterial dimensions and artery wall resonances that are induced by acoustic stimulation, which offers a direct measure of BP by a fully determined physical model. The approach and model are validated in vitro using arterial mock-ups and then in multiple arteries in human subjects. This approach offers the promise of robust continuous BP measurements, providing significant benefits for early diagnosis and treatment of cardiovascular disease.
