食事と若年層メンタルヘルスの関連性:今後の研究課題を提示 (Could dietary change support adolescent mental health? New review highlights evidence gaps and future research priorities)

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2026-01-19 スウォンジー大学

スウォンジー大学の研究チームは、思春期の精神健康に対する食事の影響を調べたレビュー研究を発表し、食習慣が若年者の心理状態に関与する可能性を示すとともに、今後の研究の課題と優先事項をまとめた。Nutrients誌掲載のレビューは、19件の研究(6件のランダム化比較試験と13件の前向きコホート研究)を分析し、栄養素単独の補給効果はまちまちであったものの、全体的に質の高い食事パターンは抑うつ症状の軽減や心理的ストレスの低減と一貫した関連がみられたと報告している。一方、現在の証拠は不一致やデモグラフィック要因の影響を受けやすく、うつ病以外の不安やストレス、自尊心などのアウトカムは十分に検討されていない。研究者らは、曝露ベースのデザイン、生物学的マーカー、標準化された評価法の導入などを含む詳細な研究ロードマップを提示し、全体的な食事アプローチの重要性を強調している。

<関連情報>

レジリエンスのレシピ:食事と青少年のメンタルヘルスに関する体系的レビュー A Recipe for Resilience: A Systematic Review of Diet and Adolescent Mental Health

Jade E. Tucker,Anthony M. Brennan,David Benton and Hayley A. Young
Nutrients  Published: 24 November 2025
DOI:https://doi.org/10.3390/nu17233677

食事と若年層メンタルヘルスの関連性:今後の研究課題を提示 (Could dietary change support adolescent mental health? New review highlights evidence gaps and future research priorities)

Highlights

What are the main findings?

  • Whole-diet patterns and quality indices showed associations with favourable mental health outcomes, whereas single-nutrient supplements yielded less reliable results.
  • Associations between diet and mental health were often sensitive to adjustment for socioeconomic status or differed by sex, indicating complex demographic interactions.

What are the implications of the main findings?

  • The findings suggest that public health and clinical strategies should prioritise whole-diet approaches over isolated supplementation for promoting adolescent mental health.
  • The review establishes a “Roadmap for Future Research” that advocates for dimensional, symptom-based assessment and biomarker-informed trial designs to overcome current methodological limitations.

Abstract

Background/Objectives: Adolescence is a critical period of vulnerability for the onset of mental health difficulties, presenting an urgent need for scalable prevention strategies. Diet is a universal, modifiable factor, yet its evidence base remains inconsistent. This systematic review synthesised evidence from controlled trials and prospective cohort studies investigating the relationship between diet and mental health in adolescents aged 10–19 years.

Methods: Searches were conducted to 20 July 2025, and risk of bias was assessed.

Results: Nineteen studies met the inclusion criteria: six intervention trials and thirteen cohort studies. Examined exposures included vitamin D, omega-3s, polyphenol-rich foods, Mediterranean-style diets, and overall diet quality. Depressive symptoms were the most studied outcome, though the synthesis also included other dimensional outcomes such as anxiety, stress, well-being, and internalising/externalising indices. Across designs, healthier dietary patterns were often associated with fewer depressive symptoms, while poorer diet quality was linked to increased psychological distress. However, the current evidence is constrained by wide variation in assessments, small samples, and significant methodological limitations—particularly with high risk or some concerns noted in half of the included intervention trials—along with evidence suggesting that associations may differ by sex and are often sensitive to adjustment for socioeconomic status. Conclusions: Despite these challenges, the findings suggest diet as a possible, actionable target for supporting adolescent mental health. This review concludes by proposing a detailed roadmap for future research, prioritising harmonised symptom-based outcomes, biomarker-verified assessments, explicit analysis of sex and socioeconomic (SES) effects, and adequately powered trials to inform effective public health strategies for youth. Protocols were registered with PROSPERO (CRD42023413970) and archived on the Open Science Framework.

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