幼少期の否定的体験が肥満リスクを高める可能性(Negative experiences may increase childhood obesity risk)

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2026-02-17 ジョージア大学(UGA)

ジョージア大学の研究によると、幼少期の否定的体験(家庭内不和や経済的不安など)が、将来的な肥満リスクの上昇と関連する可能性が示された。大規模データ解析の結果、心理的ストレスや不安定な生活環境が食行動や代謝、ホルモン応答に影響し、体重増加につながる傾向が確認された。特に複数の逆境体験を持つ子どもほどリスクが高まる傾向がみられた。研究は、肥満予防には栄養や運動だけでなく、子どもの心理社会的環境への支援が重要であることを強調している。

<関連情報>

ラテン系およびヒスパニック系の若者における有害体験、保護因子、および肥満 Adverse Experiences, Protective Factors, and Obesity in Latinx and Hispanic Youths

Victoria Goldman, MD; Sevan Esaian, PhD; Miguel Ángel Rivas Fernández, PhD;et al
JAMA Network Open  Published:December 4, 2025
DOI:10.1001/jamanetworkopen.2025.47104

幼少期の否定的体験が肥満リスクを高める可能性(Negative experiences may increase childhood obesity risk)

Key Points

Question Do youth self-reported protective factors moderate the association of adverse childhood experiences (ACEs) with body mass index (BMI) in Latinx and Hispanic youths?

Findings In this cross-sectional study of 5435 youths from the Adolescent Brain Cognitive Development (ABCD) study, ACEs were associated with increased BMI. Youth-reported self-coping skills and perceived caregiver support moderated the association of ACEs with BMI among Latinx and Hispanic youths, who had a greater number of ACEs and higher BMI than non-Hispanic youths.

Meaning These findings suggest that ACEs may increase youth obesity risk, but promotion of resiliency-focused skills may help improve pediatric weight trajectories among disproportionately impacted populations.

Abstract

Importance Pediatric obesity rates are rising, and adverse childhood experiences (ACEs) may contribute by promoting stress-induced weight gain. Few studies have examined the association of ACEs with body mass index (BMI) and youth-reported protective factors, particularly among Latinx and Hispanic youths, who face higher rates of ACEs and obesity.

Objective To evaluate the association of ACEs with BMI in a population-based cohort and determine whether youth-reported protective factors (eg, self-coping skills, caregiver or friend support, or overall support) moderate this association, with a focus on Latinx and Hispanic youths.

Design, Setting, and Participants This large, cross-sectional study of youths aged 11 to 12 years was conducted using year 2 data (July 2018 to March 2020) of the Adolescent Brain Cognitive Development (ABCD) study, a prospective, 10-year longitudinal, 21-site dataset comprised of a population-cohort of US youths. Data were analyzed between August 2024 and March 2025.

Exposures Cumulative ACEs (12 categories) and youth-reported protective factors (4 categories).

Main Outcome and Measures The primary outcome was the ability of self-reported protective factors to moderate the hypothesized association of ACEs with BMI in Latinx and Hispanic youths. Linear mixed-effects models explored associations of ACEs, protective factors, and ethnicity (ie, Latinx and Hispanic or non-Hispanic) with BMI, while controlling for confounders (eg, sex, age, puberty, and socioeconomic status).

Results There were 5435 youths with available data at ages 11 to 12 years (1141 Latinx and Hispanic [21.0%]; 2636 female [48.5%]; mean [SD] age, 143.1 [7.6] months). Compared with non-Hispanic youths, Latinx and Hispanic youths had greater BMI (mean [SD], 22.1 [5.0] vs 20.3 [4.6]; P < .001) and more ACEs (mean [SD], 2.1 [1.7] vs 1.7 [1.7]; P < .001). Across all youths, ACEs were significantly associated with BMI, with a 0.431 BMI increase for every 1.7-point increase (1 SD) in ACE score. In Latinx and Hispanic youths only, self-coping (β = -0.74; 95% CI, -1.03 to -0.46; P < .001), caregiver support (β = -0.38; 95% CI, -0.66 to -0.11; P = .006), and overall protective score (β = -0.55; 95% CI, -0.61 to -0.06; P < .001) moderated the association of ACEs with BMI.

Conclusions and Relevance These findings highlight the clinical importance of early ACE screening to identify at-risk youths for targeted, trauma-informed weight management interventions, and gather support for the cultivation of resiliency-focused skills like self-coping and caregiver support. Pediatric obesity is a pressing public health issue, and these strategies hold potential to alter weight trajectories, which may improve health outcomes and reduce health disparities.

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