2023-04-19 マックス・プランク研究所
高血圧の治療に新しいアプローチを取るために、心理的要因がどのように高血圧の治療を複雑にしているかについての新しい考え方が必要だという。うつ病と高血圧という普遍的な病気に対する新しい治療法や予防法に焦点を当て、心理的健康と身体的健康の相互作用に注目することが必要である。
<関連情報>
- https://www.mpg.de/20163652/0413-nepf-how-high-blood-pressure-affects-mental-health-149575-x
- https://www.nature.com/articles/s41467-023-37579-6
メンタルヘルス、血圧、高血圧発症の関連性 Associations between mental health, blood pressure and the development of hypertension
H. Lina Schaare,Maria Blöchl,Deniz Kumral,Marie Uhlig,Lorenz Lemcke,Sofie L. Valk & Arno Villringer
Nature Communications Published:07 April 2023
DOI:https://doi.org/10.1038/s41467-023-37579-6
Abstract
Multiple studies have reported a link between mental health and high blood pressure with mixed or even contradictory findings. Here, we resolve those contradictions and further dissect the cross-sectional and longitudinal relationship between mental health, systolic blood pressure, and hypertension using extensive psychological, medical and neuroimaging data from the UK Biobank. We show that higher systolic blood pressure is associated with fewer depressive symptoms, greater well-being, and lower emotion-related brain activity. Interestingly, impending hypertension is associated with poorer mental health years before HTN is diagnosed. In addition, a stronger baseline association between systolic blood pressure and better mental health was observed in individuals who develop hypertension until follow-up. Overall, our findings offer insights on the complex relationship between mental health, blood pressure, and hypertension, suggesting that—via baroreceptor mechanisms and reinforcement learning—the association of higher blood pressure with better mental health may ultimately contribute to the development of hypertension.
