2023-07-10 バッファロー大学(UB)
◆研究者は、約300人の参加者を対象に調査を行い、THC-O-acetateの使用による幻覚体験を評価しました。結果は、幻覚体験はほとんどなかったことを示しています。そのため、THC-O-acetateに関する幻覚体験の主張は信憑性に欠けている可能性があります。また、製品には汚染物質が含まれている場合もあり、公衆衛生上の懸念も指摘されています。
<関連情報>
- https://www.buffalo.edu/news/releases/2023/07/thc-o-acetate.html
- https://www.tandfonline.com/doi/abs/10.1080/02791072.2023.2230573
THC-O-アセテート: サイケデリックなカンナビノイドの希少な証拠 THC-O-Acetate: Scarce Evidence for a Psychedelic Cannabinoid
Daniel J. Kruger,Carlton CB Bone, Meredith C. Meacham, Charles Klein, & Jessica S. Kruger
Journal of Psychoactive Drugs Published:29 Jun 2023
DOI:https://doi.org/10.1080/02791072.2023.2230573
ABSTRACT
There is a growing interest in semi-synthetic cannabinoids, including THC-O-acetate (THC-Oac). Some cannabis marketers and users have claimed that THC-Oac produces psychedelic effects; the current study is the first to examine this claim. Researchers developed an online survey for THC-Oac consumers based on previous cannabis and psychedelic use surveys and in consultation with the moderator of an online forum. The survey assessed the experiential profile of THC-Oac and included items from the Mystical Experience Questionnaire (MEQ), an instrument for assessing psychedelic experiences. Participants reported a low to moderate level of cognitive distortions (altered sense of time, difficulties concentrating, difficulties with short-term memory) and few visuals or hallucinations. Participants’ responses were significantly below the threshold for a complete mystical experience on all four MEQ dimensions. Participants who had used classic (5-HT2A agonist) psychedelics had lower scores on all MEQ dimensions. When asked directly, 79% responded that using THC-Oac is “not at all” or “a little” of a psychedelic experience. Some reports of psychedelic experiences may be due to expectations or contaminants. Those having prior experience with classic psychedelics had lower ratings of mystical experiences.
