2023-12-01 カリフォルニア工科大学(Caltech)
◆この技術は、エルゴードリック・リレーを導入することで必要なセンサーの数を削減し、単一トランスデューサーを使用して6,400のトランスデューサー相当のデータを収集可能に。PACTERは3D画像生成にも対応し、常時キャリブレーションが不要。ワン博士によれば、エコー問題の回避に遅延線を追加することで、この技術が実現された。
<関連情報>
- https://www.caltech.edu/about/news/advancements-make-laser-based-imaging-simpler-and-three-dimensional
- https://www.nature.com/articles/s41551-023-01149-4
単一素子検出器を用いたシングルショット光音響トモグラフィによる血流動態の超高速縦断イメージング Ultrafast longitudinal imaging of haemodynamics via single-shot volumetric photoacoustic tomography with a single-element detector
Yide Zhang,Peng Hu,Lei Li,Rui Cao,Anjul Khadria,Konstantin Maslov,Xin Tong,Yushun Zeng,Laiming Jiang,Qifa Zhou & Lihong V. Wang
Nature Biomedical Engineering Published:30 November 2023
DOI:https://doi.org/10.1038/s41551-023-01149-4
Abstract
Techniques for imaging haemodynamics use ionizing radiation or contrast agents or are limited by imaging depth (within approximately 1 mm), complex and expensive data-acquisition systems, or low imaging speeds, system complexity or cost. Here we show that ultrafast volumetric photoacoustic imaging of haemodynamics in the human body at up to 1 kHz can be achieved using a single laser pulse and a single element functioning as 6,400 virtual detectors. The technique, which does not require recalibration for different objects or during long-term operation, enables the longitudinal volumetric imaging of haemodynamics in vasculature a few millimetres below the skin’s surface. We demonstrate this technique in vessels in the feet of healthy human volunteers by capturing haemodynamic changes in response to vascular occlusion. Single-shot volumetric photoacoustic imaging using a single-element detector may facilitate the early detection and monitoring of peripheral vascular diseases and may be advantageous for use in biometrics and point-of-care testing.
