2024-08-20 ミネソタ大学
<関連情報>
- https://cse.umn.edu/college/news/adaptive-3d-printing-system-pick-and-place-bugs-and-other-organisms
- https://onlinelibrary.wiley.com/doi/10.1002/advs.202404617
吸引支援適応戦略によって可能になる3Dプリント生物 3D Printed Organisms Enabled by Aspiration-Assisted Adaptive Strategies
Guebum Han, Kanav Khosla, Kieran T. Smith, Daniel Wai Hou Ng, JiYong Lee, Xia Ouyang, John C. Bischof, Michael C. McAlpine
Advanced Science Published: 21 June 2024
DOI:https://doi.org/10.1002/advs.202404617
Abstract
Devising an approach to deterministically position organisms can impact various fields such as bioimaging, cybernetics, cryopreservation, and organism-integrated devices. This requires continuously assessing the locations of randomly distributed organisms to collect and transfer them to target spaces without harm. Here, an aspiration-assisted adaptive printing system is developed that tracks, harvests, and relocates living and moving organisms on target spaces via a pick-and-place mechanism that continuously adapts to updated visual and spatial information about the organisms and target spaces. These adaptive printing strategies successfully positioned a single static organism, multiple organisms in droplets, and a single moving organism on target spaces. Their capabilities are exemplified by printing vitrification-ready organisms in cryoprotectant droplets, sorting live organisms from dead ones, positioning organisms on curved surfaces, organizing organism-powered displays, and integrating organisms with materials and devices in customizable shapes. These printing strategies can ultimately lead to autonomous biomanufacturing methods to evaluate and assemble organisms for a variety of single and multi-organism-based applications.
