超加工食品は2型糖尿病患者にとって特有の危険をもたらす(Ultra-Processed Foods Pose Unique Dangers for People With Type 2 Diabetes)

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2024-10-17 テキサス大学オースチン校(UT Austin)

超加工食品は2型糖尿病患者にとって特有の危険をもたらす(Ultra-Processed Foods Pose Unique Dangers for People With Type 2 Diabetes)

テキサス大学オースティン校の研究によると、超加工食品(ダイエットソーダやクラッカーなど)の摂取は、2型糖尿病患者の血糖コントロールを悪化させることが明らかになりました。特に、これらの食品の添加物がヘモグロビンA1C(HbA1C)レベルの上昇に関連しており、加工度の低い食品の摂取が血糖コントロールに好影響を与えることが示されています。この研究は、糖尿病患者の食事指導において、超加工食品の制限が重要であることを示唆しています。

<関連情報>

アフリカ系米国人の成人2型糖尿病患者における食品加工の程度と血糖コントロールとの関連: TX STRIDE臨床試験からの知見 Degree of Food Processing is Associated with Glycemic Control in African American Adults with Type 2 Diabetes: Findings from the TX STRIDE Clinical Trial

Erin A. Hudson, JD ∙ Jaimie N. Davis, PhD, RD ∙ Keally Haushalter∙ … ∙ Susan K. Dubois, MD ∙ Mary A. Steinhardt, EdD msteinhardt@austin.utexas.edu ∙ Marissa Burgermaster, PhD
Journal of the Academy of Nutrition and Dietetics  Published:October 8, 2024
DOI:https://doi.org/10.1016/j.jand.2024.10.007

Abstract

Background
Type 2 diabetes mellitus (T2DM) disproportionately affects African American (AA) populations. Despite the importance of diet in diabetes management, the association of diet quality and/or the degree of food processing with glycemic control in AA adults with T2DM remains unclear.

Objective
This study aimed to examine associations between diet quality scores and the degree of processing in the diet with HbA1c in AA adults with T2DM.

Design
This cross-sectional study used baseline data from participants in TX STRIDE (Texas Strength Through Resilience in Diabetes Education), an ongoing clinical trial.

Participants/setting
Participants involved in this analysis (n=273) were AA adults with T2DM recruited through local churches in Austin, TX, and the surrounding areas from August 2020 through April 2023.

Main outcome measures
Participants provided two 24-hour dietary recalls (one weekend and one weekday) and a blood sample to measure HbA1c. Healthy Eating Index-2015, Alternate Healthy Eating Index-2010, and Alternate Mediterranean Diet scores were calculated. The NOVA method was used to calculate the percentage of grams and calories that came from ultra-processed foods (UPF) and unprocessed or minimally processed foods (U/MPF).

Statistical analyses performed
Linear regression and ANOVA models tested associations between the diet quality scores and degree of food processing with HbA1c, adjusting for demographic covariates. Models were stratified by insulin use after finding a significant interaction with UPF and U/MPF.

Results
Regression analyses revealed that the percentage of grams in the total diet from UPF was positively associated with HbA1c (βadj =0.015, Padj =0.032) while U/MPF was inversely associated with HbA1c (βadj = -0.014, Padj =0.043). There was no significant association between any diet quality score and HbA1c.

Conclusions
In AA adults with T2DM, only the degree of food processing was associated with HbA1c. Future research should explore whether a causal relationship exists between food processing and HbA1c and investigate mechanisms by which UPFs may affect glycemic control.

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