医療AIで多数の異種医療画像を解析 診断支援精度が3.04%向上~「パッチベース処理×Mixture of Experts」技術で医療画像診断を革新~

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2025-06-16 早稲田大学

医療AIで多数の異種医療画像を解析 診断支援精度が3.04%向上~「パッチベース処理×Mixture of Experts」技術で医療画像診断を革新~

早稲田大学の研究チームは、多様な医療画像を1つのAIモデルで高精度に解析する新技術「PatchMoE」を開発しました。画像をパッチ単位に分割し、3次元の位置情報を保持する手法と、Mixture of Experts(MoE)を組み合わせることで、異なる解像度・構造をもつ医療画像の干渉を抑えながら学習可能にしました。4種の医療データで検証し、従来法より平均Diceスコアで3.04%向上。多施設間で活用可能な汎用的診断支援AIへの応用が期待されます。

<関連情報>

医療画像セグメンテーションのための混合データセットに対する専門家の混合によるパッチコントラスト学習の実施 Conducting patch contrastive learning with mixture of experts on mixed datasets for medical image segmentation

Jiazhe Wang,Osamu Yoshie & Yuya Ieiri
Neural Computing and Applications  Published:08 May 2025
DOI:https://doi.org/10.1007/s00521-025-11234-1

Abstract

Medical image segmentation is critical for accurate diagnosis, treatment planning, and surgical navigation. In recent years, large multitask segmentation models have often struggled due to the limited size of datasets and significant variability in target structures, image resolutions, and annotation standards. These variations can introduce task competitions during multitask model training, which hinder effective feature learning. To address these challenges, we propose PatchMoE, a unified framework designed to compensate for resolution discrepancies across datasets and feature conflicts arising in mixed-dataset training. PatchMoE is the first to introduce patch-based contrastive learning into medical image segmentation tasks, which divides images into equal-sized patches represented in 3D coordinate space. This novel approach ensures that mixed datasets with varying resolutions can be trained in a unified manner, preserving spatial relationships and enhancing contextual understanding. PatchMoE also incorporates a mixture of experts (MoE) mechanism into the decoder, which dynamically selects dataset-specific expert combinations. This design mitigates parameter conflicts through network sparsification, effectively resolving optimization conflicts in multitask datasets. The effectiveness of the proposed method was demonstrated in four independent segmentation tasks: retinal vessel (DRIVE), near-infrared blurred vessel (HVNIR), abdominal multiorgan (Synapse), and polyp segmentation (Kvasir-SEG). We compared performance using multiple metrics, including Dice score, Intersection over Union (IoU), and Hausdorff distance (HD). Compared with the state-of-the-art (SOTA) GCASCADE model, PatchMoE achieved an improvement of 3.04% in the mean Dice score across all tasks. The proposed method also achieved an average Dice score improvement of 0.88% compared to four independently trained SOTA models for each individual task. In summary, PatchMoE combines patch-based contrastive learning with dataset-informed expert gating to provide promising solutions for dataset conflicts in large transformer-based medical segmentation models.

医療・健康
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