ソフトロボットによる気管挿管装置が命を救う可能性(UCSB-designed soft robot intubation device could save lives)

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2025-09-10 カリフォルニア大学サンタバーバラ校(UCSB)

カリフォルニア大学サンタバーバラ校の研究チームは、緊急医療に不可欠な気管挿管を容易にするソフトロボット式デバイス「Soft Robotic Intubation System(SRIS)」を開発した。従来の挿管は高度な技術を要し、現場での失敗は患者の命に直結する。SRISは柔らかいチューブが先端から「成長」して気道に沿って進む仕組みで、硬い器具と異なり組織損傷のリスクを減らす。実験では専門家は100%成功し、処置時間も平均21秒と従来機器の半分以下だった。さらに救急隊員など非専門家でも短時間の訓練で高い成功率(初回87%、最終96%)を達成。簡便かつ迅速で安全な特性から、救急現場や軍事医療、資源の限られた地域での応用が期待されている。現在、臨床試験とFDA承認取得に向けた準備が進められている。

ソフトロボットによる気管挿管装置が命を救う可能性(UCSB-designed soft robot intubation device could save lives)
Photo Credit:Courtesy Image
An illustration of how the intubation device is used

<関連情報>

迅速かつ自律誘導型挿管のためのソフトロボティクスデバイス A soft robotic device for rapid and self-guided intubation

David A. Haggerty, James R. Cazzoli, Marvin A. Wayne, Christopher J. Winckler, […] , and Elliot W. Hawkes
Science Translational Medicine  Published:10 Sep 2025
DOI:https://doi.org/10.1126/scitranslmed.ads7681

Editor’s summary

Endotracheal intubation requires extensive training and clear anatomical visualization, making it challenging during emergencies, where first-pass failure rates are high. Here, Haggerty et al. developed a soft robotic device that guides a breathing tube into the trachea, reducing the need for extensive specialized training. Testing of the device by prehospital medical professionals showed the soft robotic device’s improved success and intubation duration compared with the gold-standard video laryngoscope. The findings suggest that this device could enable improved outcomes, broader use of intubation in emergency settings, and use by a broader segment of medical personnel and warrants further clinical evaluation. —Molly Ogle

Abstract

Endotracheal intubation is a critical medical procedure for protecting a patient’s airway. Current intubation technology requires extensive anatomical knowledge, training, technical skill, and a clear view of the glottic opening. However, all of these may be limited during emergency care for trauma and cardiac arrest outside the hospital, where first-pass failure is nearly 35%. To address this challenge, we designed a soft robotic device to autonomously guide a breathing tube into the trachea with the goal of allowing rapid, repeatable, and safe intubation without the need for extensive training, skill, anatomical knowledge, or a glottic view. During initial device testing with highly trained users in a mannequin and a cadaver, we found a 100% success rate and an average intubation duration of under 8 s. We then conducted a preliminary study comparing the device with video laryngoscopy, in which prehospital medical providers with 5 min of device training intubated cadavers. When using the device, users achieved an 87% first-pass success rate and a 96% overall success rate, requiring an average of 1.1 attempts and 21 s for successful intubation, significantly (P = 0.008) faster than with video laryngoscopy. When using video laryngoscopy, the users achieved a 63% first-pass success rate and a 92% overall success rate, requiring an average of 1.6 attempts and 44 s for successful intubation. This preliminary study offers directions for future clinical studies, the next step in testing a device that could address the critical needs of emergency airway management and help democratize intubation.

医療・健康
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