術前の歩行速度が人工股関節手術後の成績のカギ〜1.0m/秒以上で良好な回復 手術時期やリハビリの新しい目安に〜

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2025-12-01 九州大学

九州大学病院の研究グループは、人工股関節置換術(THA)を受けた274名を対象に、術前の身体機能と術後成績の関連を詳細に解析し、術前歩行速度1.0m/秒以上が良好な術後成績の重要指標であることを世界で初めて明らかにした。評価には患者自身が回答する患者立脚型アウトカム(PRO)と、満足度を示すPASS指標、さらに機械学習(K-meansクラスタリング)を用いて術後成績のグループを分類し、多角的に検証した。その結果、歩行速度1.0m/秒以上で手術を受けた患者は、痛み・機能・違和感のいずれにおいても成績が良好である傾向が示された。歩行速度は股関節の可動域や筋力とも強く関連しており、簡便に測定できることから、手術時期判断の新基準として、また術前リハビリにおける**具体的な目標設定(1.0m/秒の達成)**として活用できる可能性が高い。本成果は、より計画的で予後改善につながるTHA医療の実現に寄与する。

術前の歩行速度が人工股関節手術後の成績のカギ〜1.0m/秒以上で良好な回復 手術時期やリハビリの新しい目安に〜
図1:術後の股関節の痛み・機能・違和感に関するアンケート結果を基に、患者さんを3つのグループに分類した図 【緑のグループ(Cluster 1):痛みが少なく、機能が高く、股関節の違和感がほとんどない、成績が最も良好なグループ 青のグループ(Cluster 2):成績が中程度のグループ 赤のグループ(Cluster 3):成績が最も低いグループ】

<関連情報>

人工股関節全置換術後の患者報告アウトカムの予測因子としての術前歩行速度 患者の許容可能な症状状態とK平均クラスタリング分析からの洞察 Preoperative Gait Speed as a Predictor of Patient-Reported Outcomes After Total Hip Arthroplasty Insights from Patient Acceptable Symptom State and K-Means Clustering Analyses

Nakao, Yuki MD; Hamai, Satoshi MD, PhD; Yamate, Satoshi MD, PhD; Konishi, Toshiki MD; Kawahara, Shinya MD, PhD; Motomura, Goro MD, PhD; Utsunomiya, Takeshi MD, PhD; Nakashima, Yasuharu MD, PhD
The Journal of Bone & Joint Surgery  Published:November 26, 2025
DOI:10.2106/JBJS.25.00542

Abstract

Background:

Total hip arthroplasty (THA) is a well-established procedure for hip osteoarthritis (OA); however, its clinical outcomes are variable, and the optimal timing for surgery remains unclear. Identifying the preoperative predictors that influence midterm patient-reported outcome measures (PROMs) could improve patient outcomes.

Methods:

This retrospective cohort study included 274 Asian patients who underwent primary THA for OA between 2012 and 2018, who completed preoperative physical assessments, and who responded to a postoperative mail survey. Preoperative variables included symptom duration, pain intensity, hip range of motion, lower-limb muscle strength, and 10-m free gait speed. PROMs were assessed using the Oxford Hip Score (OHS) and the Forgotten Joint Score-12 (FJS-12). Clinically meaningful outcomes were assessed using the Patient Acceptable Symptom State (PASS), defined as a score of ≥42 for the OHS and a score of ≥50 for the FJS-12. Additionally, K-means clustering was applied to categorize patients into an excellent outcome group and a control group on the basis of their PROMs.

Results:

Multivariable regression analysis revealed that preoperative gait speed significantly predicted both the OHS and FJS-12 outcomes (p < 0.01). Furthermore, hip flexion range of motion and hip flexion strength were significantly associated with preoperative gait speed (p < 0.01). A receiver operating characteristic (ROC) curve analysis identified a gait speed cutoff value of 0.7 m/s for achieving the PASS for the OHS (area under the curve [AUC]: 0.69; p < 0.01) and a cutoff value of 1.0 m/s for achieving the PASS for the FJS-12 (AUC: 0.60; p = 0.01). K-means clustering identified preoperative gait speed as the sole significant predictor of classification into the excellent outcome group (odds ratio, 5.85; p < 0.01). The ROC curve analysis revealed a gait speed cutoff value of 1.0 m/s for classification into the excellent group (AUC: 0.64; p < 0.01).

Conclusions:

Preoperative gait speed, which reflects decreased mobility due to hip joint dysfunction, was a significant predictor of midterm PROMs after THA. Maintaining a preoperative gait speed of 1.0 m/s could serve as a critical threshold for achieving favorable postoperative outcomes, regardless of patient age.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

医療・健康
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