2026-01-14 早稲田大学
図1:“眼圧を無線で測る”スマートコンタクトレンズ
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パリティタイム対称無線技術を用いた統合型スマートコンタクトレンズによる眼圧の超高感度リアルタイムモニタリング Ultra-sensitive real-time monitoring of intraocular pressure with an integrated smart contact lens using parity-time symmetry wireless technology
Te Xiao,Hanzhe Zhang,Taiki Takamatsu,Atsushige Ashimori,Saman Azhari,Kazuhiro Kimura & Takeo Miyake
npj Flexible Electronics Published:13 January 2026
DOI:https://doi.org/10.1038/s41528-025-00507-3
Abstract
In recent years, smart contact lenses as a type of wearable device have attracted significant attention in health monitoring and disease detection. In this study, we combine a resistive sensor based on a cracked PEDOT: PSS structure with a 70 MHz double-loop gold antenna, enabling high-precision and continuous measurement of intraocular pressure (IOP). By comprehensively optimizing the sensor design, device structure, and wireless detection system, we achieved a sensitivity of 47.31 Ω/mmHg—approximately 15 times higher than conventional approach, corresponding to a resistance change 183 times larger. Both in vitro wireless IOP measurements of a porcine eye and in vivo wireless IOP measurements of rabbit eyes altered by microbead injection, using a commercial tonometer and a fabricated sensor lens, showed a strong correlation with R² values of 93% and 97%, respectively. These findings highlight the platform’s potential for long-term, non-invasive IOP monitoring, thus making a significant contribution to early diagnosis and treatment of glaucoma.
