2026-03-04 ワシントン州立大学（WSU）
＜関連情報＞
- https://news.wsu.edu/press-release/2026/03/04/researchers-develop-beating-3d-printed-heart-model-for-surgical-practice/
- https://advanced.onlinelibrary.wiley.com/doi/10.1002/admt.70885
左心房の解剖学的構造と統合センサーを備えた3Dプリントの動的心臓モデルで、端から端までの修復と逆流の軽減を実現 3D-Printed Dynamic Heart Model With Left-Side Anatomy and Integrated Sensor for Edge-to-Edge Repair and Regurgitation Reduction
Alejandro Guillen Obando, Hongyi Shen, Myles McGovern, Yusen Zhang, Vivien Lin, Darryl Fu, Ryan Baumwart, Kaiyan Qiu
Advanced Materials Technologies Published: 26 February 2026
DOI:https://doi.org/10.1002/admt.70885
ABSTRACT
Heart disease remains a major cause of morbidity and mortality in the United States, accounting for roughly 20% of all deaths. Minimally invasive procedures have been used to treat cardiovascular diseases; however, the heart’s anatomical complexity and dynamics require proper hands-on training on patient-specific presurgical models to reduce procedural errors. Existing dynamic heart models often rely on animal cardiac tissues to support pumping mechanics, introducing ethical and policy concerns. Fully synthetic heart models offer an alternative by using actuation devices to reproduce cardiac circulation and contraction, yet accurately replicating the full dynamics of the heart remains challenging. This research presents a 3D-printed dynamic heart model representing left-side anatomy (atrium, ventricle, and mitral valve) to support minimally invasive procedures. Soft material 3D-printing is employed to replicate key anatomical features. Sutures anchor the ventricle to the mitral valve, replicating chordae tendineae-like structures, adding physiological realism and structural complexity. McKibben actuators are embedded within the myocardial walls, mimicking ventricular contraction and realistic mitral valve motion. Customized flexible pressure sensors are designed and incorporated to monitor pressure changes inside the model. These novel features enable the model to function as a platform for hemodynamic studies and simulation of edge-to-edge repair to mitigate atrioventricular valve regurgitation.
