2026-03-05 東京科学大学
図1．小児期逆境体験（ACEs）と死亡リスク。男性では配偶者の存在がACEsの悪影響を緩和する。
＜関連情報＞
- https://www.isct.ac.jp/ja/news/9ymy27o09mqj#top
- https://www.sciencedirect.com/science/article/abs/pii/S0277953626000870
日本の高齢者における幼少期の有害体験と全死亡率：婚姻状況による修正6年間の前向きコホート研究 Adverse childhood experiences and all-cause mortality in older Japanese adults: a 6-year prospective cohort study, modified by marital status
Tomoki Kawahara, Yukako Tani, Katsunori Kondo, Takeo Fujiwara
Social Science & Medicine Available online: 21 January 2026
DOI:https://doi.org/10.1016/j.socscimed.2026.119012
Highlights
- ACEs showed no overall association with mortality in older Japanese adults.
- Among men, divorced/unmarried with 3+ ACEs had markedly higher mortality.
- Marriage appeared to buffer the ACE–mortality association in men.
- Findings support targeted, trauma-informed support for older single men.
Abstract
Objectives
Adverse childhood experiences (ACEs) are known to be associated with morbidity and premature death, but the association between ACEs and mortality among older people is unknown in Japan, and whether marital status modifies the associations remains unclear.
Methods
We analyzed data from 12,698 older adults (65+ years) participating in the Japan Gerontological Evaluation Study (JAGES; response rate 70.3 %) in 2013 and were followed for 6 years. ACEs and marital status were assessed at baseline, and mortality was prospectively followed. Cox proportional hazards models were used to assess the association between ACEs and mortality, stratified by sex and marital status adjusted for covariates.
Results
1948 deaths occurred during the follow-up (Men: 1,238, Women: 710). We found no association between ACEs and mortality overall for both sexes. When stratified by marital status, among divorced/unmarried men, those having 3+ ACEs were 4.00 times more likely to die (95 % CI: 1.46–10.95), although there was no association between ACEs and mortality among married men. In contrast, among divorced/unmarried women, having ACEs showed a lower risk of mortality, and married women also showed no association between ACEs and mortality.
Discussion
ACEs were associated with mortality among divorced/unmarried older men, which is not true for married men and all women. Further research is warranted to elucidate the mechanism to prevent the adverse effect of ACEs on mortality among divorced/unmarried men and all women.
