小児および若年層におけるCovid-19ワクチン摂取に関する新たな研究が発表される(New study provides insights into Covid-19 vaccine uptake among children and young people)

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2024-03-19 スウォンジー大学

イギリス全土で行われた研究によると、子供や若者のCOVID-19ワクチン接種率は低く、特に2回目やブースター接種ではさらに低いことが明らかになった。5歳から17歳の340万人以上の子供と若者を対象にしたこの研究では、未接種の世帯に住む子供や若者が接種率が低かったことや、12歳から15歳の年齢層が最も低かったことが示された。これは、将来のパンデミックに備えて特定のリスク要因に対処し、子供や若者へのワクチン接種を優先することの重要性を強調している。

<関連情報>

3,433,483人の子供と若者のCOVID-19ワクチン接種率:英国の前向きコホートのメタ分析 Uptake of COVID-19 vaccinations amongst 3,433,483 children and young people: meta-analysis of UK prospective cohorts

Sarah J. Aldridge,Utkarsh Agrawal,Siobhán Murphy,Tristan Millington,Ashley Akbari,Fatima Almaghrabi,Sneha N. Anand,Stuart Bedston,Rosalind Goudie,Rowena Griffiths,Mark Joy,Emily Lowthian,Simon de Lusignan,Lynsey Patterson,Chris Robertson,Igor Rudan,Declan T. Bradley,Ronan A. Lyons,Aziz Sheikh & Rhiannon K. Owen
Nature Communications  Published:15 March 2024
DOI:https://doi.org/10.1038/s41467-024-46451-0

小児および若年層におけるCovid-19ワクチン摂取に関する新たな研究が発表される(New study provides insights into Covid-19 vaccine uptake among children and young people)

Abstract

SARS-CoV-2 infection in children and young people (CYP) can lead to life-threatening COVID-19, transmission within households and schools, and the development of long COVID. Using linked health and administrative data, we investigated vaccine uptake among 3,433,483 CYP aged 5–17 years across all UK nations between 4th August 2021 and 31st May 2022. We constructed national cohorts and undertook multi-state modelling and meta-analysis to identify associations between demographic variables and vaccine uptake. We found that uptake of the first COVID-19 vaccine among CYP was low across all four nations compared to other age groups and diminished with subsequent doses. Age and vaccination status of adults living in the same household were identified as important risk factors associated with vaccine uptake in CYP. For example, 5–11 year-olds were less likely to receive their first vaccine compared to 16–17 year-olds (adjusted Hazard Ratio [aHR]: 0.10 (95%CI: 0.06–0.19)), and CYP in unvaccinated households were less likely to receive their first vaccine compared to CYP in partially vaccinated households (aHR: 0.19, 95%CI 0.13–0.29).

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