2025-07-17 イェール大学
<関連情報>
- https://news.yale.edu/2025/07/17/young-adults-improved-sleep-incentive-drink-less
- https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2834652
若年成人のアルコール使用リスクと睡眠のためのウェアラブル介入 ランダム化臨床試験 Wearable Intervention for Alcohol Use Risk and Sleep in Young Adults A Randomized Clinical Trial
Lisa M. Fucito, PhD; Garrett I. Ash, PhD; Ran Wu, MS; et al
JAMA Open Network Published:May 30, 2025
DOI:10.1001/jamanetworkopen.2025.13167
Key Points
Question Is a wearable feedback and coaching intervention efficacious for improving at-risk drinking and sleep health in young adults?
Findings In this phase 2 randomized clinical trial including 120 young adults, a 2-session multimodal sleep-alcohol wearable feedback and coaching intervention did not significantly reduce total drinks compared with web-based advice alone or with smartphone self-monitoring. All conditions had clinically meaningful drinking reductions over time, but the intervention showed a benefit over advice alone for other sleep health and drinking reduction outcomes.
Meaning These findings suggest that further research is warranted to optimize the intervention and evaluate its efficacy for alcohol risk reduction in young adults.
Abstract
Wearable Intervention for Drinking Risk and Sleep in Young Adults
Visual Abstract.
Abstract
Importance Young adults in the US have the highest prevalence of alcohol use disorder; technology-based interventions may help to reduce drinking.
Objective To test the efficacy of a multimodal digital intervention of wearable feedback and coaching for improving at-risk drinking and sleep health in young adults.
Design, Setting, and Participants This parallel phase 2 randomized clinical trial was conducted from December 17, 2018, to May 19, 2021, at a research clinic in Connecticut. Participants were young adults (aged 18-25 years) from the local community (web and social media ads, public flyers) with sleep concerns, 3 or more heavy drinking occasions (≥5 drinks/occasion for men; ≥4 drinks/occasion for women) in the past 2 weeks, and a positive Alcohol Use Disorders Identification Test risk score. Analyses were conducted from November 10, 2023, to September 19, 2024, using an intention-to-treat approach.
Interventions Wearable feedback and coaching plus web-based sleep advice plus smartphone self-monitoring or 1 of 2 control conditions, consisting of advice alone (control A) or advice plus self-monitoring (control A plus SM) for 2 weeks and follow-up to week 12. All participants wore sleep and alcohol biosensors.
Main Outcomes and Measures The primary outcome consisted of total number of drinks in weeks 4 to 12. Secondary outcomes included sleep disturbance, sleep-related impairment, and alcohol-related consequences in weeks 4 to 12. An exploratory outcome was also assessed, reduction of 1 or more levels in World Health Organization (WHO) drinking risk from baseline to week 4. Models compared the wearable feedback and coaching with advice and self-monitoring with each control condition and changes from weeks 4 to 8 and 12 within each condition on baseline-adjusted outcomes.
Results A total of 120 participants were enrolled (61 [51%] women; 10 [8%] Asian; 9 [8%] Black; 19 [16%] Hispanic; 96 [80%] White; 1 [1%] multiracial; 4 [3%] other race or ethnicity), with a mean (SD) age of 21.16 (1.75) years. Sixty participants were randomized to the intervention, 30 to the control A group and 30 to the control A plus SM group. Total number of drinks (primary outcome) did not differ by condition or by condition × time, but number of drinks was significantly higher at weeks 4 vs 12 (49%) across conditions. For secondary outcomes, no condition effects were observed for drinking consequences and sleep disturbance, but sleep-related impairment and WHO risk-level reduction (exploratory outcome) differed by condition. Compared with the control A group, the intervention group reported clinically meaningful lower sleep-related impairment scores (mean [SE] least square mean difference, 3.09 [1.08]; 95% CI, 0.96-5.23) and were more than 3 times more likely to have reductions in WHO risk level (odds ratio, 3.85; 95% CI, 1.34-11.07; Cohen d = 0.72). Sleep disturbance improvement was associated with WHO risk-level reduction.
Conclusions and Relevance This randomized clinical trial did not detect a significant effect of the intervention on the primary outcome of total drinks or secondary outcomes of sleep disturbance or drinking consequences. The intervention significantly improved other measures of sleep health and drinking reduction compared with the control A condition and warrants further testing in larger samples.
Trial Registration ClinicalTrials.gov Identifier: NCT03658954
