長距離・広角センシング可能な生分解性ソフトインプラントの開発 (Researchers Develop Soft Biodegradable Implants for Long-distance and Wide-angle Sensing)

2026-01-23 中国科学院(CAS)

<関連情報>

• https://english.cas.cn/newsroom/research_news/phys/202601/t20260122_1146420.shtml
• https://www.nature.com/articles/s41586-025-09874-3

長距離・広角センシングのための柔らかい生分解性インプラント Soft biodegradable implants for long-distance and wide-angle sensing

Yuqun Lan,Shuang Li,Haitao Guo,Qinyuan Liu,Tairan Wang,Lianqiao Zhou,Jiahuiyu Fang,Yang Zhao,Zanxin Zhou,Qi Wang,Jing Li,Yiping Zhu,Rongfang Su,Xinyi Wen,Xinkai Xu,Yuhong Wu,Zixuan Wang,Bo Liu,Jiaqi Li,Hui Li,Hanfei Gao,Yuchen Wu,Qi Gu,Xi-Qiao Feng,… Yewang Su
Nature  Published:07 January 2026
DOI:https://doi.org/10.1038/s41586-025-09874-3

Abstract

Monitoring internal physiological signals is essential for effective medical care¹, yet most current technologies rely on external measurements or imaging systems that cannot capture enough deep-tissue dynamics^2,3,4,5,6. Implantable devices offer a solution, but conventional designs often require batteries or magnets^7,8,9,10,11, which carry risks during removal, and existing biodegradable sensors based on passive inductor–capacitor circuits are limited by short readout distances and unstable communication issues^{12,13,14,15,16,17,18,19}. Here we describe a soft, biodegradable, wireless sensing device that can monitor pressure, temperature and strain over long distances (up to 16 cm), maintaining accuracy across varying positions and angles. This is achieved through a ‘pole-moving sweeping’ readout system combined with a folded structure that integrates mechanical flexibility with electromagnetic function. In vivo tests in the abdominal cavity of horses reliably captured deep-tissue pressure and temperature, and ex vivo measurements demonstrated accurate strain monitoring without strict positional control. The long-distance and wide-angle readout of soft biodegradable implants holds translational promise for accessing deep-tissue physiological signals.