暑さで1日の水の代謝回転はどう変わる? -高齢者の水代謝を二重標識水法で解明-

ad

2026-03-13 東北大学

東北大学の山田陽介教授らの研究グループは、体内の水の動きを高精度で測定する二重標識水法を用い、高齢者の水代謝が暑さによってどのように変化するかを調査した。京都府亀岡市の65歳以上の高齢者26人を対象に春(平均19℃)と夏(平均29℃)を比較した結果、夏季には体内の水の代謝回転量が1日あたり約640mL増加することが明らかになった。一方で身体活動量やエネルギー消費量は平均的に低下したが、活動量を維持している人ほど水代謝も増える傾向が見られた。猛暑が増える社会において、高齢者の適切な水分補給量の指針づくりに重要な知見となる。

暑さで1日の水の代謝回転はどう変わる? -高齢者の水代謝を二重標識水法で解明-
図1. 高齢者における春と夏の水の代謝回転と身体活動の比較
春(平均19℃)と夏(平均29℃)における体内の水の代謝回転量と身体活動量を比較したものです。夏には水の代謝回転量が増加する一方で、身体活動量は低下する傾向がみられました。

<関連情報>

自由生活を送る高齢者の春から夏にかけての水分補給、水分必要量、エネルギーバランス:二重標識水研究 Hydration, water requirements, and energy balance from spring to summer in free-living older adults: a doubly labelled water study

Hyeon-Ki Kim,Yui Nakayama,Tsukasa Yoshida,Keiichi Yokoyama,Yuya Watanabe,Aya Itoi,Eiichi Yoshimura,Hinako Nanri,Rie Tsutsumi,Yumi Nakamura,Norifumi Tateishi,Rei Ono,Misaka Kimura,Hiroyuki Sagayama & Yosuke Yamadafor the Kyoto-Kameoka Study Group
Scientific Reports  Published:19 February 2026
DOI:https://doi.org/10.1038/s41598-026-38832-w   Unedited version

Abstract

The escalating effects of climate change, particularly global warming, are posing an increasing burden on human health. Older adults are particularly susceptible to the impact of extreme heat. Adequate water intake is essential to prevent dehydration in hot environments. Therefore, it is important to understand water turnover (WT) and intake. WT of older adults in hot environments remains unknown. This study aimed at investigating the seasonal effects on WT, total energy expenditure (TEE), and physical activity using doubly labeled water (DLW) and a triaxial accelerometer. A total of 26 older Japanese adult males and females aged ≥ 65 years participated in the study. WT and TEE were measured using DLW in May and August 2012. The mean values of maximum, mean, and minimum temperatures and mean humidity of the measurement days were 24 °C, 19 °C, 14 °C, and 57% in May (spring) and 35 °C, 29 °C, 25 °C, and 66% in August (summer) 2012, respectively. The mean (standard deviation, SD) age of the participants was 73.7 (5.4) years. Total body water increased significantly from 31.1 (4.6) to 31.9 (5.2) kg (+ 0.8 kg, P = 0.009) from May to August. TEE decreased significantly from 2271 (280) to 2123 (470) kcal/day (- 149 kcal/d, P = 0.036), while WT increased significantly from 2.939 (0.625) to 3.579 (0.943) L/day (+ 0.640 L/d, P < 0.001). WT increased by 640 mL/day during summer compared to that during spring, when the average temperature was 19 °C. Our findings indicate that WT increases during hot weather in older adults, reflecting seasonal adaptation.

医療・健康
ad
ad
Follow
ad
タイトルとURLをコピーしました