2022-06-20 テキサス大学オースチン校(UT Austin)
電子タトゥーは、センサーを包む粘着性、伸縮性のある素材に存在するため、長時間装着しても快適で、滑らないので、モバイル血圧モニタリングの手段として理にかなっているのです。
この装置は、皮膚に電流を流し、生体インピーダンスと呼ばれる体の反応を分析することで測定を行います。生体インピーダンスと血圧の変化には相関があり、それは血液量の変化と関係があるのです。
<関連情報>
- https://news.utexas.edu/2022/06/20/blood-pressure-e-tattoo-promises-continuous-mobile-monitoring/
- https://www.nature.com/articles/s41565-022-01145-w
グラフェン生体インピーダンスタトゥーによる動脈血圧の継続的なカフレスモニタリングContinuous cuffless monitoring of arterial blood pressure via graphene bioimpedance tattoos
Dmitry Kireev,Kaan Sel,Bassem Ibrahim,Neelotpala Kumar,Ali Akbari,Roozbeh Jafari & Deji Akinwande
Nature Nanotechnology Published:20 June 2022
DOI:https://doi.org/10.1038/s41565-022-01145-w
Abstract
Continuous monitoring of arterial blood pressure (BP) in non-clinical (ambulatory) settings is essential for understanding numerous health conditions, including cardiovascular diseases. Besides their importance in medical diagnosis, ambulatory BP monitoring platforms can advance disease correlation with individual behaviour, daily habits and lifestyle, potentially enabling analysis of root causes, prognosis and disease prevention. Although conventional ambulatory BP devices exist, they are uncomfortable, bulky and intrusive. Here we introduce a wearable continuous BP monitoring platform that is based on electrical bioimpedance and leverages atomically thin, self-adhesive, lightweight and unobtrusive graphene electronic tattoos as human bioelectronic interfaces. The graphene electronic tattoos are used to monitor arterial BP for >300 min, a period tenfold longer than reported in previous studies. The BP is recorded continuously and non-invasively, with an accuracy of 0.2 ± 4.5 mm Hg for diastolic pressures and 0.2 ± 5.8 mm Hg for systolic pressures, a performance equivalent to Grade A classification.