自己申告による口腔の健康と全身的な健康結果との間に相関関係があることを示す研究(Study Shows Correlation Between Self-Reported Oral Health and Systemic Health Outcomes)

ad

2024-03-04 タフツ大学

新しい研究では、自己報告された口腔保健の問題が歯周病の診断と同様に、長期的な全身の健康に否定的な影響を与えることが示された。研究者は、自己報告された口腔保健データを分析し、心血管疾患や糖尿病などの合併症との関連性を調査した。これは、歯科医の診察が制限されている場合に、一般的な健康状態に関する情報を得る上で有用である可能性を示唆している。

<関連情報>

自己申告による口腔の健康状態は、全身の健康状態および全死因死亡率と関連している Self-reported oral health is associated with systemic health outcomes and all-cause mortality

Yau-Hua Yu, DMD, DMSc :Bjorn Steffensen, DDS, PhD:Daniel I. Chasman, PhD:Julie E. Buring, ScD
The Journal of the American Dental Association  Published:January 24, 2024
DOI:https://doi.org/10.1016/j.adaj.2023.11.006

Abstract

Background
Self-reported oral health questions (OHQs) are used commonly for epidemiologic surveillance of periodontal disease (PD). The authors’ objective was to investigate how OHQs are associated with well-established systemic comorbidities of PD and their impact on all-cause mortality. The authors hypothesized that OHQs exhibit associations with systemic comorbidities similar to PD.

Methods
Two independent data sets were used to achieve these objectives: the Women’s Health Study, a prospective cohort of women 45 years or older with self-reported information on PD, OHQs, cardiovascular disease, diabetes, and osteoporosis in various timeframes (continuous from 1992) and the National Health and Nutrition Examination Survey (NHANES), with data on OHQs and linked mortality (1999-2018). The authors applied multivariate logistic regression models and Cox proportional hazard regression survival analyses to test their hypotheses.

Results
The Women’s Health Study participants who reported having PD until 2006 were more likely to later report deteriorating oral health, bone loss around their teeth, or periodontal treatment in 2018. Self-rated fair or poor oral health was independently associated with increased risk of cardiovascular disease (odds ratio, 1.39; 95% CI, 1.14 to 1.69; P < .001), diabetes (odds ratio, 1.21; 95% CI, 1.02 to 1.43; P = .028), and osteoporosis (odds ratio, 1.60; 95% CI, 1.38 to 1.84; P < .001). National Health and Nutrition Examination Survey participants who self-rated fair or poor oral health had higher risks of all-cause mortality (hazard ratio, 1.18; 95% CI, 1.02 to 1.37; P = .027).

Conclusions
Self-reported oral health had a similar magnitude of associations with systemic comorbidities as established with PD previously. Moreover, self-rated fair or poor oral health, suboptimal dental visits, or infrequent flossing were associated with increased all-cause mortality.

Practical Implications
These results support the use of OHQs in assessing systemic connections, especially when clinical dental access is limited. This clinical trial was registered at ClinicalTrials.gov. The registration number is NCT00000479.

医療・健康
ad
ad
Follow
ad
タイトルとURLをコピーしました