「求愛行動」遺伝子、2種のミバエで異なる作用を示す(‘Courtship’ Gene Shows Different Effects in Two Fruit Fly Species)

ad

2024-03-21 ノースカロライナ州立大学(NCState)

ショウジョウバエの求愛行動に関連する遺伝子は、異なるショウジョウバエ種での機能が異なることが明らかになった。これは、保存遺伝子が種を越えて同じ機能を持たないことを示唆し、種や行動によって遺伝子の影響を理解する必要性を強調している。特に、Drosophila virilisの研究では、遺伝子のコピー数が求愛行動に及ぼす影響に注目されている。

<関連情報>

多様なショウジョウバエ種間の求愛行動の特定における無果実の役割 The role of fruitless in specifying courtship behaviors across divergent Drosophila species

CHRISTA A. BAKER , XIAO-JUAN GUAN , MINSEUNG CHOI , AND MALA MURTHY
Science Advances  Published:13 Mar 2024
DOI:https://doi.org/10.1126/sciadv.adk1273

「求愛行動」遺伝子、2種のミバエで異なる作用を示す(‘Courtship’ Gene Shows Different Effects in Two Fruit Fly Species)

Abstract

Sex-specific behaviors are critical for reproduction and species survival. The sex-specifically spliced transcription factor fruitless (fru) helps establish male courtship behaviors in invertebrates. Forcing male-specific fru (fruM) splicing in Drosophila melanogaster females produces male-typical behaviors while disrupting female-specific behaviors. However, whether fru’s joint role in specifying male and inhibiting female behaviors is conserved across species is unknown. We used CRISPR-Cas9 to force FruM expression in female Drosophila virilis, a species in which males and females produce sex-specific songs. In contrast to D. melanogaster, in which one fruM allele is sufficient to generate male behaviors in females, two alleles are needed in D. virilis females. D. virilis females expressing FruM maintain the ability to sing female-typical song as well as lay eggs, whereas D. melanogaster FruM females cannot lay eggs. These results reveal potential differences in fru function between divergent species and underscore the importance of studying diverse behaviors and species for understanding the genetic basis of sex differences.

細胞遺伝子工学
ad
ad
Follow
ad
タイトルとURLをコピーしました