AI活用の痛みのない乳房画像診断システムの臨床初期試験(Study: Quick, pain-free breast imaging system shows promise in early clinical tests)

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2025-07-10 バッファロー大学

AI活用の痛みのない乳房画像診断システムの臨床初期試験(Study: Quick, pain-free breast imaging system shows promise in early clinical tests)
The system under development, called OneTouch-PAT, allows women to stand and comfortably receive scans in under one minute.

バッファロー大学の研究チームは、痛みのない乳がん検査装置「OneTouch‑PAT」を開発した。光音響と超音波を組み合わせ、乳房を軽く押し当てるだけで60秒以内に高解像度の3D画像を取得可能。初期臨床試験では主要な乳がんサブタイプも識別でき、AIによる自動画像処理で診断精度も向上。従来のマンモグラフィーの課題(圧迫の痛みや感度低下)を克服する可能性があり、将来の乳がん早期発見に貢献すると期待される。

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立位ポーズでの乳房のワンタッチ自動光音響・超音波イメージング OneTouch Automated Photoacoustic and Ultrasound Imaging of Breast in Standing Pose

Huijuan Zhang; Emily Zheng; Wenhan Zheng; Chuqin Huang; Yunqi Xi; Yanda Cheng,…
IEEE Transactions on Medical Imaging  Published:12 June 2025
DOI:https://doi.org/10.1109/TMI.2025.3578929

Abstract:

We developed an automated photoacoustic and ultrasound breast tomography system that images the patient in the standing pose. The system, named OneTouch-PAT, utilized linear transducer arrays with optical-acoustic combiners for effective dual-modal imaging. During scanning, subjects only need to gently attach their breasts to the imaging window, and co-registered three-dimensional ultrasonic and photoacoustic images of the breast can be obtained within one minute. Our system has a large field of view of 17 cm by 15 cm and achieves an imaging depth of 3 cm with sub-millimeter resolution. A three-dimensional deep-learning network was also developed to further improve the image quality by improving the 3D resolution, enhancing vasculature, eliminating skin signals, and reducing noise. The performance of the system was tested on four healthy subjects and 61 patients with breast cancer. Our results indicate that the ultrasound structural information can be combined with the photoacoustic vascular information for better tissue characterization. Representative cases from different molecular subtypes have indicated different photoacoustic and ultrasound features that could potentially be used for imaging-based cancer classification. Statistical analysis among all patients indicates that the regional photoacoustic intensity and vessel branching points are indicators of breast malignancy. These promising results suggest that our system could significantly enhance breast cancer diagnosis and classification.

医療・健康
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