量子光学技術により網膜疾患診断につながる視覚現象を高精度化(Quantum optics may turn this rare visual phenomenon into an eye test)

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2026-07-09 バッファロー大学(UB)

ニューヨーク州立大学バッファロー校(University at Buffalo)の研究チームは、人間の視覚が量子レベルの光をどのように知覚するかを調べるための新しい「量子視力検査(Quantum Eye Test)」を開発した。研究では、単一光子や極めて少数の光子を精密に制御して被験者に提示し、人間が光を知覚する最小限界や知覚のばらつきを高精度で測定できる実験手法を構築した。これにより、従来の視覚検査では評価できなかった網膜の感度や神経応答を量子光学の観点から解析できるようになり、人間の視覚系が量子ゆらぎにどの程度影響されるかを検証する新たな基盤が整った。また、この手法は量子センサーや量子イメージング技術の評価基準として利用できるほか、網膜疾患の超早期診断や視覚機能評価への応用も期待される。研究成果は、量子物理学と神経科学を結び付ける新しい研究領域を切り開くものであり、生体の感覚機能を量子レベルで理解するための重要な一歩となる。

量子光学技術により網膜疾患診断につながる視覚現象を高精度化(Quantum optics may turn this rare visual phenomenon into an eye test)
llustration of the enhanced Boehm’s brush patterns observed during a University at Buffalo-led study. Researchers used a quantum optics technique to make the normally faint visual phenomenon easier to see. Photo: Dusan Sarenac/University at Buffalo

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構造化光によるベームブラシの位相的拡張 Topological expansion of Boehm’s brushes via structured light

Dmitry A. Pushin, Iman Salehi, Amy Chow, +9 , and Dusan Sarenac
Proceedings of the National Academy of Sciences  Published:July 9, 2026
DOI:https://doi.org/10.1073/pnas.2532243123

Abstract

We report an entoptic phenomenon in which the classical two-lobed Boehm’s brushes are transformed into a multilobed structure by projecting spin–orbit-coupled light onto the human retina. These structured beams, composed of nonseparable superpositions of circular polarization and orbital angular momentum, produce azimuthally modulated entoptic patterns through polarization-dependent scattering in the retina. Unlike Haidinger’s brushes, which arise from dichroic absorption in the macula, the observed effect is driven by angular variations in scattering strength relative to the local polarization direction. In regions where scattering centers exhibit polarization orientations that converge toward a common point, their combined contributions reinforce one another, producing brighter and more sharply defined entoptic lobes whose number and orientation vary systematically with the topology of the spin–orbit stimulus. Psychophysical measurements across retinal eccentricities from 0.5° to 4° in eleven participants revealed that contrast detection thresholds decreased exponentially with eccentricity, consistent with polarization-sensitive scattering by isotropic structures in the nonfoveal retinal regions. From the psychophysical fits, the mean eccentricity at which the entoptic pattern reached a 50% threshold was r50=1.03° with a 95% CI of [0.72, 1.34]°, indicating that the spin–orbit-induced entoptic structure becomes perceptually robust at approximately 1° retinal eccentricity and that perception improves with increasing retinal eccentricity. Together, these findings demonstrate that spin–orbit light modulates scattering-based visual phenomena in previously unrecognized ways, enabling approaches for probing retinal structure and visual processing using topological features of light.

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