患者に優しい処方箋ラベルが服薬アドヒアランスを向上させる(Patient-friendly prescription labels improve medication adherence)

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薬を処方通りに飲まなかったために、毎年10万人以上の方が亡くなっています More than 100,000 people die each year from not taking medications as prescribed

2023-03-14 ジョージア大学 (UGA)

UGAの新しい研究によると、処方薬のラベルを微調整することが、医師が意図した通りに患者が薬を服用するのに役立つ可能性があることがわかりました。例えば、薬を服用するタイミングやアルコールの禁止など、明確な指示を記載した処方ラベルは、高血圧薬、避妊薬、喘息薬などの服薬遵守を大幅に改善することができるという結果が出ました。
研究者たちは、改善された処方薬ラベルが患者が高い水準の服薬忠実度に到達し、それによって健康上の利益を享受するのに役立つことが分かりました。高血圧薬、避妊薬、喘息コントローラーを服用している参加者は、服薬忠実度が最大28%向上しました。

<関連情報>

地域の薬局における患者中心の処方薬ラベルのアドヒアランスへの影響 Impact of patient-centered prescription medication labels on adherence in community pharmacy

Henry N. Young,Farah S. Pathan,Stan Hudson.David Mott/Paul D. Smith,Kenneth G. Schellhase
Journal of the American Pharmacists Association  Published:January 09, 2023
DOI:https://doi.org/10.1016/j.japh.2023.01.004

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Abstract

Background
Prescription medication labels are often constructed in a manner which hinders safe and appropriate use of medicines. The United States Pharmacopeia released voluntary standards to revise medication labels in an effort to support patients’ understanding and improve medication use.

Objective
To examine the impact of label changes on medication adherence before and after pharmacy implementation of the United States Pharmacopeia patient-centered prescription medication label standards.

Methods
This study used a retrospective pre-post cohort design. Prescription fill claims data were obtained from a community health plan serving Medicaid patients for 1 independent community pharmacy organization across 8 retail pharmacy sites. We calculated medication possession ratios (MPR) and proportion of days covered (PDC) for medications used for contraception, asthma, hypertension, and depression from 15 months before to 13 months after implementation of the label changes.

Results
Findings showed significant increases in mean MPR for asthma controller (increased by 0.111 [t = 0.290, P<0.0001]), antihypertensives (increased by 0.062 [t = 0.146, P < 0.0002]), and contraceptives medications (increased 0.133 [t = 0.209, P < 0.0001]) from preintervention to postintervention periods. Results also revealed increases in mean PDC for asthma controllers (increased by 0.193 [t = 0.267, P < 0.0001]), antihypertensives (increased by 0.067 [t = 0.175, P = 0.049]), and contraceptives (increased by 0.111 [t = 0.208, P < 0.0119]) from preintervention to postintervention periods.

Conclusion
We report an association between a change to more patient-centered prescription medication labels and increased medication adherence based on MPR and PDC among Medicaid recipients.

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有機化学・薬学
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