2024-05-13 マックス・プランク研究所
<関連情報>
- https://www.mpg.de/21914270/0513-zuch-pr-underwood-2024-en-151220-x?c=2249
- https://www.nature.com/articles/s41588-024-01750-6
ハイブリッド作物のクローン性配偶子を利用して倍数体ゲノムを構築する Harnessing clonal gametes in hybrid crops to engineer polyploid genomes
Yazhong Wang,Roven Rommel Fuentes,Willem M. J. van Rengs,Sieglinde Effgen,Mohd Waznul Adly Mohd Zaidan,Rainer Franzen,Tamara Susanto,Joiselle Blanche Fernandes,Raphael Mercier & Charles J. Underwood
Nature Genetics Published:13 May 2024
DOI:https://doi.org/10.1038/s41588-024-01750-6
Abstract
Heterosis boosts crop yield; however, harnessing additional progressive heterosis in polyploids is challenging for breeders. We bioengineered a ‘mitosis instead of meiosis’ (MiMe) system that generates unreduced, clonal gametes in three hybrid tomato genotypes and used it to establish polyploid genome design. Through the hybridization of MiMe hybrids, we generated ‘4-haplotype’ plants that encompassed the complete genetics of their four inbred grandparents, providing a blueprint for exploiting polyploidy in crops.
