慢性的な孤独は若年成人の認知機能に悪影響を及ぼす可能性(Chronic loneliness may harm cognitive health in young adults)

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2025-05-29 ペンシルベニア州立大学(PennState)

ペンシルベニア州立大学の研究チームは、25~65歳の若年・中年成人を対象にした2年間の縦断研究で、慢性的な孤独感が認知機能の低下と関連することを明らかにしました。参加者はスマートフォンアプリを用いた「脳トレゲーム」を1日5回、2週間にわたり実施しました。その結果、慢性的な孤独感を抱える人々は、繰り返しの練習による認知機能の向上が見られず、他の参加者と比較して認知能力の改善が乏しいことが示されました。この現象は、将来的な神経変性疾患の初期兆候である可能性があり、慢性的な孤独感が早期のリスク因子となることが示唆されます。研究者は、孤独感の軽減には社会的支援が重要であり、他者とのつながりを積極的に求めることが、生活の質と認知健康の維持に寄与すると述べています。

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慢性的な孤独と認知機能の縦断的変化 Chronic loneliness and longitudinal changes in cognitive functioning

Jee eun Kang,Lynn M. Martire,Jennifer E. Graham-Engeland,David E. Almeida & Martin J. Sliwinski
BMC Public Health  Published:29 March 2025
DOI:https://doi.org/10.1186/s12889-025-22313-2

慢性的な孤独は若年成人の認知機能に悪影響を及ぼす可能性(Chronic loneliness may harm cognitive health in young adults)

Abstract

Background

Loneliness is a worldwide concern with significant health implications that may be a significant risk factor for Alzheimer’s disease and related dementias. In light of the importance of detecting early cognitive changes and risk factors influencing cognitive health, this study examined whether chronic loneliness predicted cognitive changes among young and middle-aged adults.

Methods

This study utilizes data from a longitudinal measurement burst study spanning over two years, comprising three waves of data collection. A systematically recruited young to mid-life adult sample (25- 65 years) included 172 racially and economically diverse participants who provided information about loneliness for at least two consecutive waves. Chronic loneliness was defined based on the validated multi-item PROMIS Social Isolation scale. We assessed working memory, processing speed, and spatial memory in a measurement burst design using mobile cognitive assessments. Multilevel growth models were conducted to examine whether chronic loneliness was associated with changes in cognitive performance during the study period of up to two years.

Results

Results revealed that chronic loneliness was not associated with baseline performance of working memory, processing speed, spatial memory or global cognitive performance, but chronic loneliness was associated with differential cognitive trajectories, specifically a lack of retest related improvement. There were no significant changes in cognitive performance for the chronic loneliness group across waves, whereas significant improvements were observed in those who were not chronically lonely.

Conclusions

This study offers insights into the impact of chronic loneliness on cognitive changes in young and middle-aged adults, revealing that chronically lonely individuals did not exhibit the practice-related improvements that are commonly observed in longitudinal studies. Findings suggest the potential significance of identifying and addressing chronic loneliness promptly to prevent potential cognitive consequences of chronic loneliness.

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