両親の予測不可能な行動が最適な脳回路形成を阻害する可能性が判明(UCI research finds parents’ unpredictable behavior may impair optimal brain circuit formation)

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発達の乱れにより、精神疾患や薬物乱用への脆弱性が高まる Disrupted development increases vulnerability to mental illness, substance abuse

2022-06-02 カリフォルニア大学校アーバイン校(UCI)

カリフォルニア大学アーバイン校の研究者らは、予測不可能な親の行動や、日課の欠如、頻繁な災害などの予測不可能な環境が、子どもの最適な情動脳回路の発達を妨げ、精神疾患や薬物乱用への脆弱性を高めるという概念について先駆的な研究を行っています。
動物実験から得られた感情脳回路の形成原理と、子どもの認知発達と精神衛生への影響について述べています。

<関連情報>

感情脳回路の成熟の原理 Principles of emotional brain circuit maturation

MATTHEW T. BIRNIE AND TALLIE Z. BARAM
Science  Published:2 Jun 2022
DOI: 10.1126/science.abn4016

Abstract

The mammalian brain is organized in overlapping, intercalated circuits, and an extensive body of information has focused on the maturation of sensory (visual, auditory) and motor circuits (13). Yet, much less is known about the maturation principles of “emotional” brain circuits, including those governing reward-, stress-, and fear-related behaviors. Evidence suggests that sensory inputs from the environment during a sensitive period in early postnatal life have important effects on emotional circuit development, just as adverse or positive images, odors, and sounds influence feelings and actions in adulthood. Disrupted operation of emotional circuits underlies mental illnesses and substance use disorders. Therefore, enhanced recognition of the principles guiding the development of these circuits is important for understanding human health.

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