2025-03-14 愛媛大学
<関連情報>
- https://www.ehime-u.ac.jp/data_relese/pr_20250314_cri/
- https://www.ehime-u.ac.jp/wp-content/uploads/2025/03/pr_20250314_cri.pdf
- https://www.jstage.jst.go.jp/article/ehpm/30/0/30_24-00313/_article
日本人中高年女性における日常外来活動パターンとメタボリックシンドローム発症:東温健康調査 Patterns of daily ambulatory activity and the onset of metabolic syndrome in middle-aged and older Japanese women: the Toon Health Study
Naofumi Yamamoto , Koutatsu Maruyama, Isao Saito, Kiyohide Tomooka, Takeshi Tanigawa, Ryoichi Kawamura, Yasunori Takata, Haruhiko Osawa
Environmental Health and Preventive Medicine Published: February 28, 2025
DOI:https://doi.org/10.1265/ehpm.24-00313
Abstract
Background: This cohort study aimed to identify the accumulation patterns of objectively measured ambulatory activity (AA) variables in the middle-aged and older Japanese women and examine the relationship of these derivative patterns with onset of metabolic syndrome (MetS).
Methods: A total of 794 women (mean age: 56.2 years) provided objectively assessed AA data using a uniaxial accelerometer. The number of steps, time accumulated in light-intensity AA (LIAA) and moderate-to-vigorous intensity AA (MVAA) and the ratio of MVAA to total AA (LIAA + MVAA) were calculated. Latent profile analysis was used to identify participant groups based on their distinct AA patterns. Logistic regression models were used to assess the association of groups with the onset of MetS after adjusting for age, sex, education, alcohol habit, smoking habit, energy intake, and the number of MetS components present at baseline.
Results: Four distinct groups were identified: Group A had low levels of the AA variable; group B accumulated a certain number or more steps primarily through MVAA; group C accumulated a certain number or more steps primarily through LIAA; and group D had high level of the AA variables. Over the course of the 5-year follow-up period, 61 participants (7.7%) developed MetS. The multivariate-adjusted odds ratio (95% confidence interval) for onset of MetS in groups B, C, and D relative to group A were 0.416 (0.166–1.218), 0.451 (0.223–0.914), and 0.933 (0.365–2.382), respectively. Group C had a significantly lower odds ratio of MetS onset than group A.
Conclusion: AA patterns accumulating a certain number or more steps, regardless of the intensity of AA, may help reduce the risk of MetS compared to inactive AA patterns.
