2025-11-18 京都大学
<関連情報>
- https://www.kyoto-u.ac.jp/ja/research-news/2025-11-18
- https://www.kyoto-u.ac.jp/sites/default/files/2025-11/web_2511_Mine-5ad5cd8b2a1b27019bb924b846797d5f.pdf
- https://www.cell.com/current-biology/abstract/S0960-9822(25)01380-6
アブラナ科における気孔防御とガス交換の進化的トレードオフ Evolutionary trade-off between stomatal defense and gas exchange in Brassicaceae
Wenshang Kang ∙ Masahito Nakano ∙ Kaori Fukumoto ∙ … ∙ Akira Mine,, ∙ Xiaowei Han ∙ Kenichi Tsuda
Current Biology Published:November 17, 2025
DOI:https://doi.org/10.1016/j.cub.2025.10.037
Highlights
- Coronatine hijacks A. thaliana CYP707A1 ABA hydroxylase to override stomatal defense
- CYP707A1 drives rapid light-induced stomatal opening in A. thaliana
- C. rubella and E. salsugineum show impaired coronatine- and light-induced opening
- CYP707A1 promoter variation drives an evolutionary defense-gas exchange trade-off
Summary
Stomatal opening is crucial for gas exchange, but it unavoidably offers invasion by pathogens. In response, plants close stomata to prevent pathogen entry, while the bacterial pathogen Pseudomonas syringae pv. tomato DC3000 (Pto) produces coronatine (COR), a jasmonate (JA) mimic, to counteract this plant response. Here, we demonstrate that by COR, Pto exploits CYP707A1 activation in Arabidopsis thaliana, encoding an enzyme that degrades abscisic acid, essential for stomatal closure. Notably, COR-induction of CYP707A1 is absent in other Brassicaceae species, such as Capsella rubella and Eutrema salsugineum, rendering them resistant to Pto invasion. By contrast, in A. thaliana, CYP707A1 enables rapid stomatal opening in response to light in a JA-dependent manner, enhancing gas exchange and chlorophyll content, unlike C. rubella and E. salsugineum. Promoter-swap experiments confirm that the regulatory region of CYP707A1 underlies these evolutionary diversifications. Together, our study presents a mechanism underlying an evolutionary trade-off between stomatal defense and gas exchange.
