2025-07-21 中国科学院(CAS)
<関連情報>
- https://english.cas.cn/newsroom/research_news/life/202507/t20250721_1047737.shtml
- https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003247
長期的な音楽トレーニングは、加齢に伴うノイズの中の音声知覚における神経活動のアップレギュレーションを防ぐことができる Long-term musical training can protect against age-related upregulation of neural activity in speech-in-noise perception
Lei Zhang,Bernhard Ross,Yi Du ,Claude Alain
PLOS Biology Published: July 15, 2025
DOI:https://doi.org/10.1371/journal.pbio.3003247
Abstract
During cognitive tasks, older adults often show increased frontoparietal neural activity and functional connectivity. Cognitive reserve accrued from positive life choices like long-term musical training can provide additional neural resources to help cope with the effect of aging. However, the relationship between cognitive reserve and upregulated neural activity in older adults remains poorly understood. In this study, we measured brain activity using functional magnetic resonance imaging during a speech-in-noise task and assessed whether cognitive reserve accumulated from long-term musical training bolsters or holds back age-related increase in neural activity. Older musicians exhibited less upregulation of task-induced functional connectivity than older non-musicians in auditory dorsal regions, which predicted better behavioral performance in older musicians. Furthermore, older musicians demonstrated more youth-like spatial patterns of functional connectivity, as compared to older non-musicians. Our findings show that cognitive reserve accrued through long-term music training holds back age-related neural recruitment during speech-in-noise perception and enlighten the intricate interplay between cognitive reserve and age-related upregulated activity during cognitive tasks.
