97%のデンマーク女性が更年期症状を経験(97 percent of women in Denmark experience symptoms during menopause)

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2025-10-30 コペンハーゲン大学(UCPH)

コペンハーゲン大学公衆衛生学部のマリア・ヒブホルト准教授らは、デンマークの45〜59歳女性15万3800人を対象にした全国調査「KISOプロジェクト」を実施し、97%の女性が更年期に何らかの症状を経験していると報告した。中等度から重度の症状を少なくとも1つ持つ女性は83%、6種類以上の症状を訴える人は28%に達した。主な症状は睡眠障害(54%)、ほてり(43%)、疲労感(39%)、関節・筋肉痛(39%)、性的問題(35%)である。更年期の前段階である「周閉経期」でも54%が中等度以上の症状を示し、更年期後期でも21%が重度の症状を報告した。研究者らは「更年期は病気ではないが、公衆衛生上の重大課題であり、社会的理解と支援が必要」と指摘する。本調査は3年ごとに継続実施され、女性の健康と更年期の長期的変化を追跡する計画である。

<関連情報>

健康的な移行期にある女性(KISO)調査:デンマーク在住の45~59歳の女性153,800人のコホート Women in Healthy Transition (KISO) Survey: a cohort of 153,800 women aged 45–59 years living in Denmark

Sigrid Normann Biener,Terese Sara Høj Jørgensen & Maria Hybholt
European Journal of EpidemiologyPublished:27 August 2025
DOI:https://doi.org/10.1007/s10654-025-01291-0

97%のデンマーク女性が更年期症状を経験(97 percent of women in Denmark experience symptoms during menopause)

Abstract

The nationwide Women in Healthy Transition (KISO) Survey Cohort is a population-based longitudinal prospective cohort study established to explore the significant data gap on women’s symptoms through different stages of menopause in a Northern European context. The KISO Survey Cohort was set up to represent women aged 45–59 years living in Denmark. In total 575,863 women were invited to participate in the study at baseline. Data were collected through digital questionnaires from June to December 2024 and included self-reported information on stages of menopause, menopausal symptoms, quality of life, physical activity, and work productivity loss using validated scales as well as information on various health, social and lifestyle factors. The follow-up of the KISO Survey Cohort will be conducted through digital questionnaires every three years over a 15-year period, inviting baseline respondents and eligible women aged 45–59 at follow-up. A total of 153,800 women completed the baseline questionnaire, yielding a 27% response rate. Among the participants, 8% were in premenopause, 24% in perimenopause, and 45% in postmenopause. Moreover, 13% had induced menopause and 10% were undergoing menopausal hormone therapy. The KISO Survey Cohort is the first large-scale longitudinal study on menopausal symptoms among women in Denmark. Data are coupled with the personal identification numbers (CPR) enabling opportunities to link data to national administrative registers. This ongoing study, thus, offers unique and extensive data, enabling future research to advance our understanding of menopause, how it affects women, and its long-term effects on women.

医療・健康
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