2026-01-23 カリフォルニア工科大学(Caltech)
Hybrid rotational ultrasound and photoacoustic tomography (RUS-PAT) combines fast panoramic rotational ultrasound tomography with photoacoustic tomography to enable quasi-simultaneous 3D imaging of soft-tissue structure and vasculature. The system has been used to obtain large-field-of-view, dual-contrast imaging of multiple human anatomical regions, including the head, breast, and extremities.Credit: Yang Zhang
<関連情報>
- https://www.caltech.edu/about/news/bringing-optical-color-to-ultrasound
- https://www.nature.com/articles/s41551-025-01603-5
人体の回転超音波および光音響トモグラフィー Rotational ultrasound and photoacoustic tomography of the human body
Yang Zhang,Shuai Na,Jonathan J. Russin,Karteekeya Sastry,Li Lin,Junfu Zheng,Yilin Luo,Xin Tong,Yujin An,Peng Hu,Konstantin Maslov,Tze-Woei Tan,Charles Y. Liu & Lihong V. Wang
Nature Biomedical Engineering Published:16 January 2026
DOI:https://doi.org/10.1038/s41551-025-01603-5
Abstract
Imaging the human body′s morphological and angiographic information is essential for diagnosing, monitoring and treating medical conditions. Here we combine the power of ultrasonography for morphological assessment of soft tissue with photoacoustic tomography (PAT) for visualizing blood vessels to enable three-dimensional (3D) panoramic imaging. Specifically, fast panoramic rotational ultrasound tomography and PAT are integrated for hybrid rotational ultrasound and photoacoustic tomography (RUS-PAT), which obtains 3D ultrasound structural and PAT angiographic images of the human body quasi-simultaneously. The rotational ultrasound tomography functionality is achieved using a single-element ultrasonic transducer for ultrasound transmission and rotating arc-shaped arrays for 3D panoramic detection. By switching the acoustic source to a light source, the system is conveniently converted to PAT mode to acquire angiographic images in the same region. Using RUS-PAT, we successfully imaged the human head, breast, hand and foot with a 10-cm-diameter field of view, submillimetre isotropic resolution and 10 s imaging time for each modality. 3D RUS-PAT is a powerful tool for high-speed, dual-contrast imaging of the human body with potential for rapid clinical translation.
