2024-02-05 ロイヤルメルボルン工科大学(RMIT)
◆世界中で、これらのリスクのある薬物のリストは、医療専門家が医薬品管理と安全性を向上させるのに役立っています。リードリサーチャーのケイト・ワン博士は、「PIMsリストは、臨床医が病院入院や死亡などのネガティブな臨床転帰のリスクが高い薬物を特定するのに役立ちます」と述べています。
◆高齢者に特に重要なこれらの高リスク薬物のリストは、多くの場合、病状を管理するために複数の薬物が必要な高齢者にとって重要です。高齢者の20〜70%が少なくとも1つのPIMを処方されています。薬物に関連する副作用は、すべての予期せぬ入院の20%を占め、そのうちの半分は可能性がある限り防ぐことができるものです。
<関連情報>
- https://www.rmit.edu.au/news/all-news/2024/feb/potentially-inappropriate-medicines
- https://onlinelibrary.wiley.com/doi/10.1111/imj.16322
デルファイ法を用いてオーストラリアの潜在的に不適切な医薬品リストを作成 Development of a list of Australian potentially inappropriate medicines using the Delphi technique
Kate N. Wang, Christopher D. Etherton-Beer, Frank Sanfilippo, Amy T. Page
Internal Medicine Journal Published: 02 February 2024
DOI:https://doi.org/10.1111/imj.16322
Abstract
Background
Older people are at high risk of medicines-related harms. otentially inappropriate medicines (PIMs) list has been developed to assist clinicians and researchers to identify medicines with risks that may potentially outweigh their benefits in order to improve medication management and safety.
Aim
To develop a list of PIMs for older people specific to Australia.
Methods
The study obtained expert consensus through the utilisation of the Delphi technique in Australia. A total of 33 experts partook in the initial round, while 32 experts engaged in the subsequent round. The primary outcomes encompass medicines assessed as potentially inappropriate, the specific contexts in which their inappropriateness arises and potentially safer alternatives.
Results
A total of 16 medicines or medicine classes had one or more medicines deemed as potentially inappropriate in older people. Up to 19 medicines or medicine classes had specific conditions that make them more potentially inappropriate, while alternatives were suggested for 16 medicines or classes.
Conclusion
An explicit PIMs list for older people living in Australia has been developed containing 19 drugs/drug classes. The PIMs list is intended to be used as a guide for clinicians when assessing medication appropriateness in older people in Australian clinical settings and does not substitute individualised treatment advice from clinicians.
