磁気誘導ソフトロボットが血栓治療を安全化する可能性(Magnet-guided soft robots could lead to safer treatment of life-threatening blood clots, Concordia research shows)

ad

2026-05-26 カナダ・コンコルディア大学

Concordia University の研究チームは、磁場で遠隔操作できるソフトロボットを用いた新しい血栓治療技術を開発した。柔軟な材料で作られた微小ロボットを血管内で磁気制御し、血栓部位へ安全に到達させることで、従来治療より低侵襲かつ高精度な血栓除去を目指す。現在のカテーテル治療や薬剤療法では、血管損傷や出血リスクが課題となるが、ソフトロボットは柔軟性により血管壁への負荷を低減できる点が特徴である。研究では、血流環境下でロボットの移動制御や標的到達性能を検証し、複雑な血管経路でも安定誘導できる可能性を示した。研究者らは、脳卒中や肺塞栓症など生命を脅かす血栓疾患への応用を期待しており、将来的には低侵襲医療や精密ドラッグデリバリー技術への発展も見込まれている。

磁気誘導ソフトロボットが血栓治療を安全化する可能性(Magnet-guided soft robots could lead to safer treatment of life-threatening blood clots, Concordia research shows)
Overview of the developed robotic platform and its main subsystems, adapted from Alireza Moezi’s PhD thesis.

<関連情報>

磁場勾配下における磁気活性軟質連続体ロボットのロボット支援追跡制御 Robotic-assisted tracking control of magnetoactive soft continuum robots in magnetic gradients

Alireza Moezi, Ramin Sedaghati and Subhash Rakheja
Smart Materials and Structures  Published: 22 January 2026
DOI:10.1088/1361-665X/ae2708

Abstract

Stroke and other neurovascular disorders demand advanced biomedical technologies capable of precise operation in confined anatomical environments. Magnetoactive soft continuum robots (MSCRs) offer flexibility and magnetic responsiveness for minimally invasive interventions, yet real-time control under nonuniform magnetic fields remains challenging. This study presents a novel robotic-assisted, closed-loop feedforward–feedback proportional–integral–derivative (FFPID) control strategy for accurate tip deflection and trajectory tracking of MSCRs actuated by a rotatable permanent magnet. A nonlinear quasi-static model of the MSCR is first developed to account for the effects of magnetic torque, magnetic body force, and gravity. The model is further extended to simulate MSCR behavior in a fluidic environment, better reflecting physiological vascular conditions. The external nonuniform magnetic field generated by a permanent magnet is modeled using finite element (FE) simulations in COMSOL Multiphysics and experimentally validated. A deep neural network trained on the FE dataset is utilized to efficiently predict 2D magnetic field magnitudes and gradients, providing real-time inputs to the quasi-static model. The developed model is subsequently employed to fine-tune the coefficients of the proposed FFPID control algorithm. The MSCR is fabricated and characterized through mechanical and magnetic testing, and a dedicated experimental platform is developed to evaluate its performance in both ambient and fluidic environments under varying magnetic gradients and fluid flow rates. A multi-tracker Eye-to-Hand calibration framework is implemented to ensure magnetic field alignment. Moreover, a trained deep learning–based model is developed for MSCR detection and deformation estimation. Four hardware-in-the-loop experiments are conducted using a six-degree-of-freedom robotic arm to assess the controller’s performance across different MSCR materials and boundary configurations. The results demonstrate the robustness and precision of the proposed FFPID control strategy across various experimental conditions, including operation under different fluid flow rates. The controller consistently outperforms the conventional PID in tracking experiments, highlighting its strong potential for real-time, robot-assisted neurovascular applications.

医療・健康
ad
ad
Follow
ad
タイトルとURLをコピーしました