2026-06-11 ワシントン大学セントルイス校
＜関連情報＞
- https://source.washu.edu/2026/06/socioeconomic-factors-linked-to-lasting-imprint-in-kids-brains/
- https://www.science.org/doi/10.1126/science.aee6213
脳全体の関連性のパターンは社会経済的状況を反映している Patterns of brain-wide associations reflect socioeconomics
Scott Marek, Meghan Rose Donohue, Nicole R. Karcher, Caroline P. Hoyniak, […] , and Nico U. F. Dosenbach
Science Published:11 Jun 2026
DOI:https://doi.org/10.1126/science.aee6213
Socioeconomics is the dominant axis of childhood brain organization.
[Figure created by Lucy Reading-Ikkanda]
Abstract
Previous brain-wide association studies (BWAS) have linked specific environmental and behavioral variables to brain variability. In this work, we mapped 649 variables to children’s brains and compared the resultant BWAS maps with each other and with neurobiological reference patterns. Socioeconomic status (SES) showed the strongest brain-wide associations. The SES associations were strongest in motor and sensory but not cognitive regions, a pattern shared across many BWAS maps, including intelligence quotient (IQ). A single, common BWAS brain pattern existed across variables that was most reflective of a child’s socioeconomics. Adjusting for SES weakened brain-IQ associations, eliminating the BWAS motor and sensory pattern. Brain-with-IQ associations also did not generalize when trained on higher-SES subsamples. Thus, children’s brains vary the most with SES, potentially through SES-dependent sleep deprivation and stress.
