2022-05-11 ジョージア工科大学
ジョージア工科大学の研究者Woon-Hong Yeoとその共同研究者は、移植可能なソフト電子監視システムの開発により、患者の確率を改善しようとしている。彼らの新しいデバイスは、スマートなステントとプリントされたソフトセンサーで構成され、電池や回路を使わずに血行動態を無線でリアルタイムに監視することができるものである。
<関連情報>
- https://research.gatech.edu/georgia-tech-researchers-develop-wireless-implantable-vascular-monitoring-system
- https://www.science.org/doi/10.1126/sciadv.abm1175
血行動態を多重にセンシングするプリントソフトセンサーを用いた完全埋め込み型ワイヤレスバッテリーレス血管エレクトロニクス Fully implantable wireless batteryless vascular electronics with printed soft sensors for multiplex sensing of hemodynamics
ROBERT HERBERT,HYO-RYOUNG LIM,BRUNO RIGO AND WOON-HONG YE
Science Advances Published:11 May 2022
DOI: 10.1126/sciadv.abm1175
Abstract
The continuous monitoring of hemodynamics attainable with wireless implantable devices would improve the treatment of vascular diseases. However, demanding requirements of size, wireless operation, and compatibility with endovascular procedures have limited the development of vascular electronics. Here, we report an implantable, wireless vascular electronic system, consisting of a multimaterial inductive stent and printed soft sensors capable of real-time monitoring of arterial pressure, pulse rate, and flow without batteries or circuits. Developments in stent design achieve an enhanced wireless platform while matching conventional stent mechanics. The fully printed pressure sensors demonstrate fast response times, high durability, and sensing at small bending radii. The device is monitored via inductive coupling at communication distances notably larger than prior vascular sensors. The wireless electronic system is validated in artery models, while minimally invasive catheter implantation is demonstrated in an in vivo rabbit study. Overall, the vascular system offers an adaptable framework for comprehensive monitoring of hemodynamics.
