2026-02-02 カナダ・ブリティッシュコロンビア大学(UBC)
<関連情報>
- https://news.ubc.ca/2026/02/canadian-surgical-innovation-cuts-ovarian-cancer-risk-by-nearly-80-per-cent/
- https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2844597
日和見両側卵管切除術後の漿液性卵巣癌 Serous Ovarian Cancer Following Opportunistic Bilateral Salpingectomy
Ramlogan Sowamber, MPH; Alice J. Mei; Paramdeep Kaur, PhD:et al
JAMA Network Open Published:February 2, 2026
DOI:10.1001/jamanetworkopen.2025.57267
Introduction
Ovarian carcinoma is a heterogeneous disease with a 5-year survival rate below 50%.1 Primary prevention of the most common histotype of ovarian carcinoma (high-grade serous carcinoma [HGSC], 70% of ovarian carcinomas) is possible using opportunistic bilateral salpingectomy (OBS; the removal of the fallopian tubes during another pelvic surgery while conserving the ovaries). Significant data show that OBS is safe,2 it does not appear to reduce the age of onset of menopause,3 and it is cost-effective.4 Herein, this evidence base is expanded by (1) estimating the risk reduction for serous ovarian cancer afforded by OBS using population-based data; and (2) examining whether the histotype distribution of ovarian carcinomas in people without fallopian tubes significantly differs from the historical histotype distribution.
