2023-11-16 マサチューセッツ工科大学(MIT)
◆このパッチは膀胱を正確にイメージし、その満腹度を判定できることが実証され、これにより膀胱や腎臓の障害を抱える患者がこれらの臓器の正常な機能をより簡単に追跡できる可能性があります。
◆このアプローチは、超音波アレイの位置を変更し信号の周波数を調整することで、体内の他の臓器をモニターするためにも適応できます。このデバイスは、卵巣がんなど、体の深部に形成されるがんの早期発見を可能にする可能性があります。
<関連情報>
- https://news.mit.edu/2023/ultrasound-patch-can-measure-how-full-your-bladder-is-1116
- https://www.nature.com/articles/s41928-023-01068-x
膀胱容積モニタリング用コンフォーマブルフェーズドアレイ超音波パッチ A conformable phased-array ultrasound patch for bladder volume monitoring
Lin Zhang,Colin Marcus,Dabin Lin,David Mejorado,Scott Joseph Schoen Jr,Theodore T. Pierce,Viksit Kumar,Sara V. Fernandez,David Hunt,Qian Li,Ikra Iftekhar Shuvo,David Sadat,Wenya Du,Hannah Edenbaum,Li Jin,Weiguo Liu,Yonina C. Eldar,Fei Li,Anantha P. Chandrakasan,Anthony E. Samir & Canan Dagdeviren
Nature Electronics Published:16 November 2023
DOI:https://doi.org/10.1038/s41928-023-01068-x
Abstract
Ultrasound can be used to image soft tissues in vivo for the early diagnosis and monitoring of disease progression. However, conventional ultrasound probes are rigid, have a narrow field of view and are operator dependent. Conformable transducers have been proposed, but they lack efficient element localization and effective spatial resolution during mechanical deformations. Here we report a conformable ultrasound bladder patch that is based on multiple phased arrays embedded in a stretchable substrate and can provide mechanically robust, conformable and in vivo volumetric organ monitoring. The phased arrays use Sm/La-doped Pb(Mg1/3Nb2/3)O3–PbTiO3 ceramics as the piezoelectric material, which offers superior properties (d33 = 1,000 pC N-1, εr = 7,500 and k33 = 0.77) than conventional piezoelectric ceramics. We use the conformable ultrasound patch in a pilot clinical study of bladder monitoring. Bladder volume estimation with the patch is comparable (relative errors of 3.2 ± 6.4% and 10.8 ± 8.2% with and without ultrasound gel, respectively) to that obtained using standard clinical ultrasound equipment, and not requiring manual translation or rotation by an operator.
