2025-07-02 カナダ・ブリティッシュコロンビア大学(UBC)
<関連情報>
- https://news.ubc.ca/2025/07/orange-is-the-new-aphrodisiac-for-guppies/
- https://www.nature.com/articles/s41559-025-02781-w
ディープラーニングがグッピーの雄の色彩の複雑な遺伝的構造を明らかにする Deep learning reveals the complex genetic architecture of male guppy colouration
Wouter van der Bijl,Jacelyn J. Shu,Versara S. Goberdhan,Linley M. Sherin,Changfu Jia,Maria Cortazar-Chinarro,Alberto Corral-Lopez & Judith E. Mank
Nature Ecology & Evolution Published:01 July 2025
DOI:https://doi.org/10.1038/s41559-025-02781-w
Abstract
The extraordinary variation in male guppy (Poecilia reticulata) colouration is a powerful model for studying the interplay of natural and sexual selection. However, the complexity of this variation has hampered the high-resolution characterization and determination of the genetic architecture underlying male guppy colour and clouded our understanding of how this exceptional level of diversity is maintained. Here we identify the heritability and genetic basis of male colour variation using convolutional neural networks for high-resolution phenotyping coupled with selection experiments, controlled pedigrees and whole-genome resequencing for a genome-wide association study of colour traits. Our phenotypic and genomic results converge to show that colour patterning in guppies is a combination of many heritable features, each with a largely independent genetic architecture spanning the entire genome. Autosomally inherited ornaments are polygenic, with significant contributions from loci involved in neural crest cell migration. Unusually, the results of our genome-wide association study suggest that gene duplicates from the autosomes to the Y chromosome are responsible for much of the sex-linked variation in colour in guppies, providing a potential mechanism for the maintenance of variation of this classic model trait.
