米国消防士におけるPFAS蓄積要因を特定(New study identifies key predictors of PFAS levels in US career firefighters)

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2026-02-02 アリゾナ大学

米国のUniversity of Arizonaの研究チームは、米国の職業消防士におけるPFAS(有機フッ素化合物)曝露レベルを左右する主要因を特定した。調査では血中PFAS濃度を測定し、職務内容や装備、勤務年数との関連を分析した結果、消火活動で使用される泡消火剤への関与、耐火防護服の着用頻度、消防署での生活環境などが高濃度曝露と強く関連することが分かった。PFASは内分泌かく乱やがんとの関連が指摘されており、消防士は一般集団より高い曝露リスクにさらされている。本研究は、曝露低減策や防護装備・運用改善の科学的根拠を提供し、消防士の健康保護に重要な知見を示した。

米国消防士におけるPFAS蓄積要因を特定(New study identifies key predictors of PFAS levels in US career firefighters)
A new study provides vital insights into the factors that influence PFAS body burdens in firefighters. Understanding the predictors of PFAS accumulation is a critical step toward protecting their long-term health.Captain John Gulotta (retired)/Tucson Fire Department

<関連情報>

米国の職業消防士における血清中のパーフルオロアルキル化合物およびポリフルオロアルキル化合物(PFAS)濃度の予測因子 Predictors of serum per- and polyfluoroalkyl substances (PFAS) levels among U.S. career firefighters

Conner, Reagan MPH; Hollister, James MS; Lutrick, Karen PhD; Beitel, Shawn C. MSc; Wardenaar, Floris C. PhD; Porter, Cynthia MS; Healy, Olivia BS; Kern, Krystal J. MA; Gulotta, John J.; Valliere, Eric A. BA, COFD; Godfrey, Orion J.; Furlong, Melissa PhD; Burgess, Jefferey L. MD, MS, MPH
Journal of Occupational and Environmental Medicine  Published:January 19, 2026
DOI: 10.1097/JOM.0000000000003670

Abstract

Objective

To identify potential predictors of serum concentrations of per- and polyfluoroalkyl substances (PFAS) among a cohort of U.S. firefighters.

Methods

Serum PFAS concentrations were measured in 2,056 U.S. structural firefighters between July 2023 and October 2024. Data on demographics, lifestyle behaviors, occupational exposures, and fire agency policies were collected through individual and fire agency surveys and evaluated for associations with serum PFAS concentrations.

Results

Plasma and/or blood donation, drinking water source, military service, post-fire on-scene decontamination, turnout gear storage and transportation, rank, using aqueous film-forming foam, and carpet in fire station living quarters were all significant predictors of at least one PFAS chemical (p ≤ 0.05).

Conclusions

Both individual and departmental predictors of serum PFAS concentrations were identified. These findings can help guide the selection of PFAS exposure reduction activities by firefighters.

医療・健康
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