2026-04-30 名城大学,獨協医科大学,科学技術振興機構
図１．16個のGaN系マイクロLEDと32チャンネルのECoG電極を搭載したフレキシブルシート
＜関連情報＞
- https://www.jst.go.jp/pr/announce/20260430-3/index.html
- https://www.jst.go.jp/pr/announce/20260430-3/pdf/20260430-3.pdf
- https://iopscience.iop.org/article/10.35848/1882-0786/ae5ebe
マウスにおける広範囲双方向神経インターフェースのための柔軟なマイクロLED-皮質脳波記録シート Flexible MicroLED–electrocorticography sheet for wide-area bidirectional neural interface in mice
Kazuto Matsui, Ruri Kurogi, Takuya Hikima, Mitsuhiro Yamada, Atsushi Nishikawa, Alexander Loesing, Noriaki Ohkawa and Hiroto Sekiguchi
Applied Physics Express Published: 28 April 2026
DOI:10.35848/1882-0786/ae5ebe
Abstract
We demonstrate a flexible bidirectional neural interface integrating 16 InGaN-based MicroLEDs and 32 ECoG electrodes on a parylene C substrate via low-temperature indium bonding at 160 °C that slides epidurally from the parietal surface to the deep lateral cortex in mice without brain penetration. This is the first sheet-type device to achieve wide-area-optogenetic stimulation and -electrophysiological recording beyond the limitation only for the dorsal cortex in a rodent’s brain. In vivo experiments confirm simultaneous access to four sensory cortices through sensory-evoked responses and demonstrate optogenetic neural activation absent in a wild-type control.
