2026-05-07 イェール大学
＜関連情報＞
- https://news.yale.edu/2026/05/07/pantry-pest-control-garlic-kills-mood-mosquitoes-too
- https://www.cell.com/cell/abstract/S0092-8674(26)00338-7
植物スクリーニングにより、ニンニクに含まれる化合物がショウジョウバエと蚊の交尾および産卵を阻害することが明らかになった A phytoscreen identifies a garlic compound as a deterrent of mating and egg laying in Drosophila and mosquitoes
Shimaa A.M. Ebrahim S ∙ Gaëlle J.S. Talross ∙ Hany K.M. Dweck ∙ John J. Shepard ∙ John R. Carlson
Cell Published:April 17, 2026
DOI:https://doi.org/10.1016/j.cell.2026.03.037
Graphical abstract
Highlights
- A “phytoscreen” identifies garlic as a potent deterrent of fly and mosquito behaviors
- Diallyl disulfide, a garlic compound, inhibits mating and egg laying
- Mating and egg-laying effects depend on taste and the TrpA1 channel
- Garlic exposure increases expression of a gene that encodes a satiety hormone
Summary
One means of controlling insect disease vectors and pests is with compounds that manipulate their behavior. An extraordinary variety of phytochemicals, i.e., compounds produced by plants, activate insect chemosensory systems. Fruits and vegetables present a source of compounds that are inexpensive and safe. A “phytoscreen” of 43 fruits and vegetables identified garlic as a potent deterrent of mating and egg laying in Drosophila. Diallyl disulfide, a garlic compound, deters both behaviors. Mating and egg-laying effects depend on taste and the TrpA1 channel. Garlic inhibits mating and egg laying in Aedes vector mosquitoes and mating of the tsetse fly Glossina morsitans. Garlic exposure increases expression of Drosophila head genes, including female-specific independent of transformer (fit), which encodes a satiety hormone that is essential for the effect of garlic on egg-laying preference.
