雇用の不安定さと早期退職が認知機能低下・認知症リスクと関連(Employment Instability and Early Retirement Linked to Cognitive Deficits and Risk of Dementia)

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2026-09-23 コロンビア大学

コロンビア大学公衆衛生大学院の研究は、雇用の不安定さや早期退職と、高齢期の認知機能低下・認知症リスクとの関連を調べたものである。研究では、就業歴や退職時期などの労働状況と、その後の認知機能を分析し、安定した就業から早期に退職する場合や、雇用が不安定な状態を経験した場合に、認知機能の低下と関連する傾向が示された。研究者らは、退職そのものだけでなく、失業や雇用不安、経済的ストレス、社会的交流の変化など、職業生活を取り巻く要因が認知健康に影響する可能性を指摘している。ただし、観察研究に基づく関連性であり、雇用不安定や早期退職が直接認知症を引き起こすことを証明したものではない。この成果は、認知症予防を医学的要因だけでなく、労働・社会経済的環境を含めて考える必要性を示すものといえる。

<関連情報>

高齢期の雇用不安と労働力参加の軌跡:健康・退職研究の統一認知評価プロトコルにおける認知機能および認知障害との関連性 Trajectories of late-life job insecurity and labor force participation: Associations with cognitive function and impairment in the Health and Retirement Study’s harmonized cognitive assessment protocol

Erika T. Beidelman, Xuexin Yu, Constance Beaufils, Rachel Donnelly, Mateo Farina, Amanda Sonnega, Lindsay C. Kobayashi, Yuan S. Zhang
Alzheimer’s & Dementia  Published: 23 September 2026
DOI:https://doi.org/10.1002/alz.71863

雇用の不安定さと早期退職が認知機能低下・認知症リスクと関連(Employment Instability and Early Retirement Linked to Cognitive Deficits and Risk of Dementia)

Abstract

INTRODUCTION
Continued workforce participation may preserve later-life cognition, yet many Americans face job insecurity and instability in later life, with potential consequences for cognitive aging.

METHODS
Using Health and Retirement Study (HRS) Harmonized Cognitive Assessment Protocol data (n = 2418), we applied gender-stratified sequence analyses to identify clusters of combined employment and job insecurity trajectories (1998 to 2014). We estimated associations with domain-specific cognitive scores and impairment status in 2016 using weighted, multivariable-adjusted regression.

RESULTS
Six clusters were identified separately for women and men. Among women, self-employed, early retirement, not in labor force, and secure-to-retirement trajectories were significantly associated with lower memory and executive function scores (β range = −0.13 to −0.32 standard deviation units) compared to secure employment. Among men, inconsistent employment was associated with poorer performance across most cognitive domains compared to secure employment. Employment instability and early retirement were associated with higher odds of cognitive impairment among women.

DISCUSSION
These results underscore employment security as a potential protective factor for cognitive aging.

Highlights

  • Sequence analysis identified six distinct employment trajectories for men and women.
  • Early retirement was linked to lower executive function and memory scores in women.
  • Inconsistent employment was associated with lower cognitive scores in men.
  • Stable employment clusters were associated with better cognitive health in late life.
医療・健康
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